|
rs10455872
|
|
|
0.770 |
GeneticVariation |
BEFREE |
We genotyped the CAD-associated variants at the LPA (rs10455872) and 9p21 loci (rs1333049) in the GeneCAST (Genetics of Calcific Aortic STenosis) Consortium and conducted a meta-analysis for their association with AVS.
|
30482443 |
2019 |
|
rs10455872
|
|
|
0.770 |
GeneticVariation |
BEFREE |
The genetic variants of rs3135506 (G), rs10455872 (A) and rs3798220 (G) have low frequency in our population and reflected no association with CAD.
|
29309886 |
2018 |
|
rs10455872
|
|
G |
0.770 |
GeneticVariation |
GWASCAT |
Association analyses based on false discovery rate implicate new loci for coronary artery disease.
|
28714975 |
2017 |
|
rs10455872
|
|
|
0.770 |
GeneticVariation |
BEFREE |
We confirmed the association of the LPA rs10455872 with CAD in a large sample of Brazilian patients.
|
24776095 |
2014 |
|
rs10455872
|
|
|
0.770 |
GeneticVariation |
BEFREE |
TaqMan SNP genotyping assays were performed to detect the rs6415084, rs3798220 and rs10455872 genotypes in 517 Chinese Han patients with CAD after PCI.
|
23978127 |
2013 |
|
rs10455872
|
|
|
0.770 |
GeneticVariation |
BEFREE |
Individuals with the G allele of rs10455872, which represents approximately one in seven patients, have a higher risk of CAD than the majority of the population even after treatment with statins; and therefore represent a vulnerable group requiring an alternative medication in addition to statin treatment.
|
23903772 |
2013 |
|
rs10455872
|
|
|
0.770 |
GeneticVariation |
BEFREE |
In conclusion, heritable contributions of LPA rs10455872 and rs3798220 to Lp(a) cholesterol levels and to angiographic CAD were prospectively assessed in this study.
|
23735648 |
2013 |
|
rs10455872
|
|
|
0.770 |
GeneticVariation |
BEFREE |
It is unclear whether the LPA variants rs10455872 and rs3798220, which correlate with lipoprotein(a) levels and coronary artery disease (CAD), confer susceptibility predominantly via atherosclerosis or thrombosis.
|
22898070 |
2012 |
|
rs41272114
|
|
T |
0.710 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs74617384
|
|
|
0.710 |
GeneticVariation |
BEFREE |
We found genome-wide significant evidence for association with CAD at the previously well-established LPA locus (lead variant: rs74617384; OR 1.38 [95% CI 1.26, 1.51], p = 3.2 × 10<sup>-12</sup>) and at 9p21 (lead variant: rs10811652; OR 1.19 [95% CI 1.13, 1.26], p = 6.0 × 10<sup>-11</sup>).
|
30003307 |
2018 |
|
rs74617384
|
|
T |
0.710 |
GeneticVariation |
GWASCAT |
We found genome-wide significant evidence for association with CAD at the previously well-established LPA locus (lead variant: rs74617384; OR 1.38 [95% CI 1.26, 1.51], p = 3.2 × 10<sup>-12</sup>) and at 9p21 (lead variant: rs10811652; OR 1.19 [95% CI 1.13, 1.26], p = 6.0 × 10<sup>-11</sup>).
|
30003307 |
2018 |
|
rs41272114
|
|
|
0.710 |
GeneticVariation |
BEFREE |
The LPA null allele (rs41272114) is associated with decreased circulating lipoprotein(a) levels and decreased CAD risk.
|
24925971 |
2014 |
|
rs10755578
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Using a Chinese Han sample, which consisted of 1012 well-characterized CAD patients and 889 healthy controls, we tested the associations of four SNPs (rs2048327, rs3127599, rs7767084 and rs10755578) in the SLC22A3-LPAL2-LPA gene cluster, and their inferred haplotypes with the risk of CAD.
|
23036009 |
2012 |
|
rs7767084
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Using a Chinese Han sample, which consisted of 1012 well-characterized CAD patients and 889 healthy controls, we tested the associations of four SNPs (rs2048327, rs3127599, rs7767084 and rs10755578) in the SLC22A3-LPAL2-LPA gene cluster, and their inferred haplotypes with the risk of CAD.
|
23036009 |
2012 |
|
rs10755578
|
|
|
0.710 |
GeneticVariation |
GWASDB |
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease.
|
19198611 |
2009 |
|
rs7767084
|
|
|
0.710 |
GeneticVariation |
GWASDB |
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease.
|
19198611 |
2009 |
|
rs6926458
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study on lipoprotein (a) levels and coronary artery disease severity in a Chinese population.
|
31186284 |
2019 |
|
rs73596816
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study on lipoprotein (a) levels and coronary artery disease severity in a Chinese population.
|
31186284 |
2019 |
|
rs7770628
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study on lipoprotein (a) levels and coronary artery disease severity in a Chinese population.
|
31186284 |
2019 |
|
rs140570886
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs55730499
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs55730499
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
|
30104761 |
2018 |
|
rs73596816
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs140570886
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease.
|
28714974 |
2017 |
|
rs55730499
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |