Gene: IL4 ×
Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2243250
rs2243250
IL4
0.030 GeneticVariation BEFREE Haplotype analysis showed a significantly increased AR risk associated with the haplotype G-T-T (rs7130588-rs2155219-rs7927894) and a protective effect with the haplotype C-G-C (rs2243250-rs2227284-s2243290). 30170133

2018
dbSNP: rs2243250
rs2243250
IL4
0.030 GeneticVariation BEFREE GG/CC/CC and TT/TT/TT (rs2243248, rs2243250, and rs2070874) haplotypes in the IL-4 gene had a significant negative correlation with AR. 24075353

2014
dbSNP: rs2243250
rs2243250
IL4
0.030 GeneticVariation BEFREE rs2243250 and rs2227284 are significantly associated with asthma and allergic rhinitis. 23654077

2013
dbSNP: rs2227284
rs2227284
IL4
0.020 GeneticVariation BEFREE Haplotype analysis showed a significantly increased AR risk associated with the haplotype G-T-T (rs7130588-rs2155219-rs7927894) and a protective effect with the haplotype C-G-C (rs2243250-rs2227284-s2243290). 30170133

2018
dbSNP: rs2227284
rs2227284
IL4
0.020 GeneticVariation BEFREE rs2243250 and rs2227284 are significantly associated with asthma and allergic rhinitis. 23654077

2013
dbSNP: rs2070874
rs2070874
IL4
0.010 GeneticVariation BEFREE GG/CC/CC and TT/TT/TT (rs2243248, rs2243250, and rs2070874) haplotypes in the IL-4 gene had a significant negative correlation with AR. 24075353

2014