Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs267606998
rs267606998
RAD51C
0.800 GeneticVariation UNIPROT Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair. 24141787

2014
dbSNP: rs267606999
rs267606999
RAD51C
C 0.800 GeneticVariation CLINVAR Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair. 24141787

2014
dbSNP: rs267606999
rs267606999
RAD51C
0.800 GeneticVariation UNIPROT Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair. 24141787

2014
dbSNP: rs267606998
rs267606998
RAD51C
0.800 GeneticVariation UNIPROT Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients. 21990120

2012
dbSNP: rs267606999
rs267606999
RAD51C
C 0.800 GeneticVariation CLINVAR Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. 22167183

2012
dbSNP: rs267606999
rs267606999
RAD51C
0.800 GeneticVariation UNIPROT Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients. 21990120

2012
dbSNP: rs267606999
rs267606999
RAD51C
C 0.800 GeneticVariation CLINVAR Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716

2012
dbSNP: rs267606999
rs267606999
RAD51C
C 0.800 GeneticVariation CLINVAR Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families. 22451500

2012
dbSNP: rs267606998
rs267606998
RAD51C
0.800 GeneticVariation UNIPROT Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964

2010
dbSNP: rs267606999
rs267606999
RAD51C
C 0.800 GeneticVariation CLINVAR Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964

2010
dbSNP: rs267606999
rs267606999
RAD51C
0.800 GeneticVariation UNIPROT Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964

2010
dbSNP: rs267606998
rs267606998
RAD51C
T 0.800 SusceptibilityMutation CLINVAR

dbSNP: rs267606999
rs267606999
RAD51C
C 0.800 SusceptibilityMutation CLINVAR

dbSNP: rs770637624
rs770637624
RAD51C
T 0.700 CausalMutation CLINVAR Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene. 27913932

2017
dbSNP: rs1060502601
rs1060502601
RAD51C
A 0.700 CausalMutation CLINVAR Inherited Mutations in Women With Ovarian Carcinoma. 26720728

2016
dbSNP: rs587781410
rs587781410
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs587781995
rs587781995
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients. 26822949

2016
dbSNP: rs587782528
rs587782528
RAD51C ; TEX14
T 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs730881939
rs730881939
RAD51C
TA 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs1060502601
rs1060502601
RAD51C
A 0.700 CausalMutation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251

2015
dbSNP: rs200293302
rs200293302
RAD51C
T 0.700 CausalMutation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251

2015
dbSNP: rs587780259
rs587780259
RAD51C
G 0.700 CausalMutation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251

2015
dbSNP: rs587781410
rs587781410
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic. 26057125

2015
dbSNP: rs587781995
rs587781995
RAD51C ; LOC105371843
C 0.700 GeneticVariation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251

2015
dbSNP: rs587782528
rs587782528
RAD51C ; TEX14
T 0.700 CausalMutation CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251

2015