|
rs13361160
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The minor C-allele of rs13361160 on chromosome 5p15.2, located upstream of chaperonin-containing-TCP1-complex-5 gene (CCT5) and downstream of FAM173B, was found to be associated with a 30% higher risk of CWP (minor allele frequency=43%; OR=1.30, 95% CI 1.19 to 1.42, p=1.2×10(-8)).
|
22956598 |
2013 |
|
rs4680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The meta-analyses showed that fibromyalgia or chronic widespread pain is the only type of chronic pain that could be associated with the COMT single nucleotide polymorphism rs4680 (Val158Met).
|
22722321 |
2012 |
|
rs6476030
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no significant association between CWP and rs6476030 in individual cohorts or when combined in a fixed-effects meta-analysis (Odds Ratio = 0.96 (95% confidence interval 0.82, 1.11) p = 0.567).
|
23006801 |
2012 |
|
rs6746030
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Logistic regression (additive genetic model) was used to test for association between rs6746030 and CWP compared to controls, adjusting for study centre in EMAS.
|
23006801 |
2012 |
|
rs12584920
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was an increased likelihood of having CWP in subjects with 1 or 2 copies of the T allele of rs12584920 (odds ratio [OR] 1.64, 95% confidence interval [95% CI] 1.01-2.60 [P = 0.03] in the discovery cohort, and OR 1.46, 95% CI 1.07-2.00 [P = 0.018] in the validation cohort).
|
21305503 |
2011 |
|
rs10483639
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs forming a proposed "pain-protective" haplotype in GCH1 (rs10483639, rs3783641 and rs8007267) and two SNPs in OPRM1 (rs1777971 (A118G) and rs563649) were genotyped in cases with persistent CWP (CWP present at >or=2 time-points) and controls who were pain-free at all time-points.
|
19775452 |
2009 |
|
rs1777971
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs forming a proposed "pain-protective" haplotype in GCH1 (rs10483639, rs3783641 and rs8007267) and two SNPs in OPRM1 (rs1777971 (A118G) and rs563649) were genotyped in cases with persistent CWP (CWP present at >or=2 time-points) and controls who were pain-free at all time-points.
|
19775452 |
2009 |
|
rs1799971
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs forming a proposed "pain-protective" haplotype in GCH1 (rs10483639, rs3783641 and rs8007267) and two SNPs in OPRM1 (rs1777971 (A118G) and rs563649) were genotyped in cases with persistent CWP (CWP present at >or=2 time-points) and controls who were pain-free at all time-points.
|
19775452 |
2009 |
|
rs3783641
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs forming a proposed "pain-protective" haplotype in GCH1 (rs10483639, rs3783641 and rs8007267) and two SNPs in OPRM1 (rs1777971 (A118G) and rs563649) were genotyped in cases with persistent CWP (CWP present at >or=2 time-points) and controls who were pain-free at all time-points.
|
19775452 |
2009 |
|
rs563649
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs forming a proposed "pain-protective" haplotype in GCH1 (rs10483639, rs3783641 and rs8007267) and two SNPs in OPRM1 (rs1777971 (A118G) and rs563649) were genotyped in cases with persistent CWP (CWP present at >or=2 time-points) and controls who were pain-free at all time-points.
|
19775452 |
2009 |
|
rs6280
|
|
|
0.010 |
GeneticVariation |
BEFREE |
DRD3 Ser9Gly polymorphism is related to thermal pain perception and modulation in chronic widespread pain patients and healthy controls.
|
19464960 |
2009 |
|
rs8007267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs forming a proposed "pain-protective" haplotype in GCH1 (rs10483639, rs3783641 and rs8007267) and two SNPs in OPRM1 (rs1777971 (A118G) and rs563649) were genotyped in cases with persistent CWP (CWP present at >or=2 time-points) and controls who were pain-free at all time-points.
|
19775452 |
2009 |