|
rs10846744
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We further examined 27 parameters of interest, including Lp-PLA2 mass and activity, inflammatory markers, and plasma phospholipid fatty acids, and fatty acid ratios in participants from the Multi-Ethnic Study of Atherosclerosis (MESA), as potential mediators in the pathway linking rs10846744 with cIMT and incident CVD.
|
30289950 |
2018 |
|
rs10846744
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our analysis of the full Multi-Ethnic Study of Atherosclerosis cohort provides strong evidence for the association of rs10846744 with common carotid intimal-medial thickness (P=1.04E-4 in combined analysis of all 4 Multi-Ethnic Study of Atherosclerosis racial/ethnic groups).
|
22628436 |
2012 |
|
rs10846744
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Variation in SCARB1 at rs10846744 was significantly associated with CCIMT across racial/ethnic groups in Multi-Ethnic Study of Atherosclerosis.
|
20160195 |
2010 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Association of C3435T multi drug resistance gene-1 polymorphism with aspirin resistance in ischemic stroke and its subtypes.
|
22177087 |
2012 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The role of the single nucleotide polymorphisms (SNPs) on positions 2677G>T/A and 3435C>T of the multi-drug-resistance gene 1 (MDR1) in inflammatory bowel disease (IBD) remains unclear.
|
17665184 |
2007 |
|
rs120074192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, we assessed the influence of the KCNQ1 S140G mutation on ventricular electrophysiological stability and mechanical pumping performance using a multi-scale model of cardiac electromechanics.
|
30108508 |
2018 |
|
rs121434569
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Acquired <i>EGFR</i> T790M Mutation After Relapse Following EGFR-TKI Therapy: A Population-based Multi-institutional Study.
|
29715155 |
2018 |
|
rs2814778
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Inflammatory cytokines (IL-2, 6, and 10) in participants in the Howard University Family Study (HUFS) and Multi-Ethnic Study in Atherosclerosis (MESA) showed similar levels in individuals homozygous for the rs2814778 allele compared to others, indicating cytokine sink hypothesis played a minor role in leukocyte homeostasis.
|
29596498 |
2018 |
|
rs6570507
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis.
|
30069010 |
2018 |
|
rs5068
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A favorable cardiometabolic profile is associated with the G allele of the genetic variant rs5068 in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA).
|
29253899 |
2017 |
|
rs573951598
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four different mutations were identified in CYP27A1, including a reported pathogenic mutation for cerebrotendinous xanthomatosis (p.R405W), which was observed in six patients from a multi-incident family, three diagnosed with MS, two with an undefined neurological disease and one seemingly healthy.
|
28337550 |
2017 |
|
rs765371999
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four different mutations were identified in CYP27A1, including a reported pathogenic mutation for cerebrotendinous xanthomatosis (p.R405W), which was observed in six patients from a multi-incident family, three diagnosed with MS, two with an undefined neurological disease and one seemingly healthy.
|
28337550 |
2017 |
|
rs9540488
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The most significant SNP (rs9540488) by childhood socioeconomic status interaction within the rs9540493 gene/region was suggestively replicated in the Multi-Ethnic Study of Atherosclerosis (MESA) (<i>p</i> = 0.07).
|
28961216 |
2017 |
|
rs9540493
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The most significant SNP (rs9540488) by childhood socioeconomic status interaction within the rs9540493 gene/region was suggestively replicated in the Multi-Ethnic Study of Atherosclerosis (MESA) (<i>p</i> = 0.07).
|
28961216 |
2017 |
|
rs104893877
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study.
|
26758830 |
2016 |
|
rs1801160
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multi-SNP analysis showed that a three-SNP haplotype (Hap7) involving rs1801160, rs1801265 and rs2297595 causes a marked decrease in 5-FUDR, comparable to that caused by the splice site variant rs3918290, which is the main pharmacogenetic marker associated with severe fluorouracil toxicity.
|
26216193 |
2016 |
|
rs2043211
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic Association for P2X7R rs3751142 and CARD8 rs2043211 Polymorphisms for Susceptibility of Gout in Korean Men: Multi-Center Study.
|
27550484 |
2016 |
|
rs2297595
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multi-SNP analysis showed that a three-SNP haplotype (Hap7) involving rs1801160, rs1801265 and rs2297595 causes a marked decrease in 5-FUDR, comparable to that caused by the splice site variant rs3918290, which is the main pharmacogenetic marker associated with severe fluorouracil toxicity.
|
26216193 |
2016 |
|
rs3751142
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic Association for P2X7R rs3751142 and CARD8 rs2043211 Polymorphisms for Susceptibility of Gout in Korean Men: Multi-Center Study.
|
27550484 |
2016 |
|
rs3918290
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multi-SNP analysis showed that a three-SNP haplotype (Hap7) involving rs1801160, rs1801265 and rs2297595 causes a marked decrease in 5-FUDR, comparable to that caused by the splice site variant rs3918290, which is the main pharmacogenetic marker associated with severe fluorouracil toxicity.
|
26216193 |
2016 |
|
rs16844364
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based upon ethnicity-stratified single-variant association analysis and trans-ethnic meta-analysis of 6201 participants of the Multi-Ethnic Study of Atherosclerosis (MESA), we discovered five statistically significant common and low-frequency variants: HGF missense polymorphism rs5745687 (p.E299K) as well as four variants (rs16844364, rs4690098, rs114303452, rs3748034) within or in proximity to HGFAC.
|
25998175 |
2015 |
|
rs3748034
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based upon ethnicity-stratified single-variant association analysis and trans-ethnic meta-analysis of 6201 participants of the Multi-Ethnic Study of Atherosclerosis (MESA), we discovered five statistically significant common and low-frequency variants: HGF missense polymorphism rs5745687 (p.E299K) as well as four variants (rs16844364, rs4690098, rs114303452, rs3748034) within or in proximity to HGFAC.
|
25998175 |
2015 |
|
rs5745687
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based upon ethnicity-stratified single-variant association analysis and trans-ethnic meta-analysis of 6201 participants of the Multi-Ethnic Study of Atherosclerosis (MESA), we discovered five statistically significant common and low-frequency variants: HGF missense polymorphism rs5745687 (p.E299K) as well as four variants (rs16844364, rs4690098, rs114303452, rs3748034) within or in proximity to HGFAC.
|
25998175 |
2015 |
|
rs1049550
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The multi-SNP model reveals that rs1049550 is the only independent SNP association effect after accounting for the other two marginally associated SNPs.
|
25056970 |
2014 |
|
rs11571836
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Recently, two single nucleotide polymorphisms (SNPs; rs11571836 and rs1799943) were identified, both located in untranslated regions of chromosome 13, associated with cardiovascular disease (CVD) in a multi-ethnic population.
|
24938600 |
2014 |