Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2251214
rs2251214
0.020 GeneticVariation BEFREE Association between cognitive performance and SYT1-rs2251214 among women with cocaine use disorder. 31562556

2019

dbSNP: rs2251214
rs2251214
0.020 GeneticVariation BEFREE The association between SYT1-rs2251214 and cocaine use disorder further supports its role in psychiatry. 31059723

2019

dbSNP: rs324420
rs324420
0.010 GeneticVariation BEFREE We hypothesized that cocaine use disordered (CUD) participants with the FAAH Pro129 Thr variant would exhibit a distinct profile of cocaine-induced subjective effects in the laboratory. 30126012

2018

dbSNP: rs1386497
rs1386497
0.010 GeneticVariation BEFREE Several significant gene × environment interactions between 5-HT genotypes and cocaine use on WM emerged: in cocaine users, the long/long (5-HTTLPR), 9+10/9+10 (VNTR In2) and C/C (TPH2 rs1386497) genotypes were risk alleles for WM impairments, whereas in healthy controls these polymorphisms were associated with improved WM performance. 26013962

2015

dbSNP: rs2609997
rs2609997
0.010 GeneticVariation BEFREE In the current imaging genetics study, we investigated a single nucleotide polymorphism (SNP) of the protein-coding proenkephalin gene (PENK: rs2609997, recently shown to be associated with cannabis dependence) in 55 individuals with cocaine use disorder and 37 healthy controls. 26164485

2015

dbSNP: rs3776823
rs3776823
0.010 GeneticVariation BEFREE A meta-analysis across both samples confirmed that CAMK2A rs3776823 TT-allele carriers display a faster transition to severe cocaine use than C-allele carriers. 25290264

2014

dbSNP: rs1048101
rs1048101
0.010 GeneticVariation BEFREE We examined whether a functional variant of the ADRA1A gene (Cys to Arg at codon 347 in exon 2, Cys347Arg) may enhance treatment response through decreased stimulation of this α1A-adrenoceptor, since antagonists of this receptor show promise in reducing cocaine use. 23849431

2013

dbSNP: rs1803274
rs1803274
0.010 GeneticVariation BEFREE Our findings suggest that the AA genotype of rs1803274 is a risk factor for crack cocaine use, which is more addictive than powder cocaine use. 24312228

2013

dbSNP: rs199472730
rs199472730
0.010 GeneticVariation BEFREE In this study, we characterized a deleterious variant, KCNQ1-S277L, found in a patient who presented with sudden cardiac death in the presence of cocaine use. 21895724

2011