|
rs4442975
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Functional Variant rs4442975 Modulating FOXA1 Binding Affinity Can Influence Bone Marrow Suppression during Neoadjuvant Chemotherapy for Luminal A Type Breast Cancer.
|
30881995 |
2019 |
|
rs4415084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After grouping breast cancer subtypes, significantly reduced survival was associated with the variant alleles of rs9485372 for luminal A and rs4415084 for triple negative breast cancer.
|
30285756 |
2018 |
|
rs9485372
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After grouping breast cancer subtypes, significantly reduced survival was associated with the variant alleles of rs9485372 for luminal A and rs4415084 for triple negative breast cancer.
|
30285756 |
2018 |
|
rs2303425
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Logistic regression analysis showed that individuals with the MSH2 rs2303425 C/C genotype had a significantly increased risk of breast cancer compared to those with the T/T genotype (adjusted odds ratio 2.0; 95 % confidence interval 1.1-3.8), particularly in early-onset breast cancer patients with the luminal A subtype.
|
26975740 |
2017 |
|
rs35054928
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through a stratification analysis, <i>5q11.2/MAP3K1</i> (rs16886034, rs16886364, rs16886397, rs1017226, rs16886448) and <i>7q32.3/LINC-PINT</i> (rs4593472) were associated with Luminal A, and <i>10q26.1/FGFR2</i> (rs35054928) was associated with Luminal B.
|
28408616 |
2017 |
|
rs4593472
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through a stratification analysis, <i>5q11.2/MAP3K1</i> (rs16886034, rs16886364, rs16886397, rs1017226, rs16886448) and <i>7q32.3/LINC-PINT</i> (rs4593472) were associated with Luminal A, and <i>10q26.1/FGFR2</i> (rs35054928) was associated with Luminal B.
|
28408616 |
2017 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Premenopausal T allele carriers of the 3435 C/T polymorphism showed a 2-fold increased risk of breast cancer with respect to the reference and postmenopausal groups, as well as triple-negative expression regarding the luminal A/B molecular subrogated subtypes.
|
25730063 |
2015 |
|
rs6099128
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the race-combined analyses, rs6099128 had reduced ORs for luminal A (OR = 0.76, 95% CI = 0.60-0.95) and basal-like breast cancer (OR = 0.54, 95% CI = 0.37-0.80).
|
25328151 |
2015 |
|
rs3104746
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Several SNPs in TNRC9/TOX3 were associated with luminal A (ER/PR+, HER2-) or basal-like breast cancer (ER-, PR-, HER2-, HER1, or CK 5/6+), and one SNP (rs3104746) was associated with both.
|
24177593 |
2014 |
|
rs1416532705
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Comparing the prevalence of CHEK2 mutations in BC with controls revealed that carriers of an I157T variant had OR of 1.80 for luminal A subtype and carriers of truncating mutations had OR of 6.26 for luminal B subtype of BC.
|
21701879 |
2012 |
|
rs17879961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Comparing the prevalence of CHEK2 mutations in BC with controls revealed that carriers of an I157T variant had OR of 1.80 for luminal A subtype and carriers of truncating mutations had OR of 6.26 for luminal B subtype of BC.
|
21701879 |
2012 |