|
rs121909222
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Targeted Pten deletion plus p53-R270H mutation in mouse mammary epithelium induces aggressive claudin-low and basal-like breast cancer.
|
26781438 |
2016 |
|
rs1047972
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs (rs6014711, rs911162, rs1047972) had positive associations with basal-like breast cancer, and ORs reduced or close to 1.00 for other subtypes.
|
25328151 |
2015 |
|
rs6099128
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the race-combined analyses, rs6099128 had reduced ORs for luminal A (OR = 0.76, 95% CI = 0.60-0.95) and basal-like breast cancer (OR = 0.54, 95% CI = 0.37-0.80).
|
25328151 |
2015 |
|
rs11075995
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Of the four breast cancer subtypes, the associations of rs12493607 (3p24.1/TGFBR2) with HER-2 overexpression in breast cancer (P = 1.09 × 10(-3)) and rs11075995 (16q12.2/FTO) with basal-like breast cancer (P = 1.64 × 10(-4)) were statistically significant.
|
25007960 |
2014 |
|
rs12493607
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Of the four breast cancer subtypes, the associations of rs12493607 (3p24.1/TGFBR2) with HER-2 overexpression in breast cancer (P = 1.09 × 10(-3)) and rs11075995 (16q12.2/FTO) with basal-like breast cancer (P = 1.64 × 10(-4)) were statistically significant.
|
25007960 |
2014 |
|
rs3104746
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Several SNPs in TNRC9/TOX3 were associated with luminal A (ER/PR+, HER2-) or basal-like breast cancer (ER-, PR-, HER2-, HER1, or CK 5/6+), and one SNP (rs3104746) was associated with both.
|
24177593 |
2014 |
|
rs9436746
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Few patterns were observed among tag SNPs, with the exception of 3 LEPR SNPs (rs17412175, rs9436746, and rs9436748) that were in moderate LD and inversely associated with basal-like breast cancer.
|
21516303 |
2011 |
|
rs9436748
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Few patterns were observed among tag SNPs, with the exception of 3 LEPR SNPs (rs17412175, rs9436746, and rs9436748) that were in moderate LD and inversely associated with basal-like breast cancer.
|
21516303 |
2011 |
|
rs2070235
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also identified a significant association between the G/G genotype of a nonsynonymous B-Myb germline variant (rs2070235, S427G) and an increased risk of basal-like breast cancer [OR 2.0, 95% CI (1.1-3.8)].
|
19043454 |
2009 |