|
rs5498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, we propose that the combination of IL-6 -572C/G and ICAM-1 K469E polymorphisms have a synergistic effect on the onset of SSNHL.
|
29695657 |
2018 |
|
rs3805435
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As the result, the AG genotype of rs3805435 had an adjusted odds ratio (OR) of 0.54 (95% confidence interval = 0.37-0.79, p = 0.001) compared with the AA genotype in the SSNHL cases.
|
28738977 |
2017 |
|
rs10955255
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GRHL2 genetic polymorphisms, rs611419 and rs10955255, have a protective role against SSHL and reduce the risk of SSHL.
|
26847018 |
2016 |
|
rs611419
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Combined genotypes of rs611419, rs10955255 and rs6989650 in the GRHL2 gene are also associated with a reduced risk of SSHL (P=0.035).
|
26847018 |
2016 |
|
rs6989650
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Combined genotypes of rs611419, rs10955255 and rs6989650 in the GRHL2 gene are also associated with a reduced risk of SSHL (P=0.035).
|
26847018 |
2016 |
|
rs702553
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The TT genotype of rs702553</span> exhibited an adjusted odds ratio (OR</span>) of 3.83 (95 % confidence interval = 1.46-11.18) (p = 0.006) in female SSNHL.
|
26521189 |
2016 |
|
rs10489678
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, no significant differences were detected in either the genotype or allele frequencies of the other two SNPs, rs945635 and rs10489678, between the SSNHL and control groups.
|
26051414 |
2015 |
|
rs3761959
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results revealed a significant association between three SNPs-rs7528684, rs3761959, and rs7522061-and SSNHL in the studied Chinese Han population.
|
26051414 |
2015 |
|
rs7522061
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results revealed a significant association between three SNPs-rs7528684, rs3761959, and rs7522061-and SSNHL in the studied Chinese Han population.
|
26051414 |
2015 |
|
rs7528684
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five single-nucleotide polymorphisms (SNPs) in FCRL3-rs945635, rs3761959, rs7522061, rs10489678, and rs7528684-were genotyped in 630 patients with SSNHL and 600 healthy controls by using a PCR-restriction fragment length polymorphism assay.
|
26051414 |
2015 |
|
rs755622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to explore the association between the MIF (-173 G/C) polymorphism (rs755622) and SSNHL in an Iranian population.
|
26426302 |
2015 |
|
rs1387153
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease in individuals with polymorphisms in the genes: methionine synthase (MTR; rs1805087); methionine-synthase reductase (MTRR; rs1801394); nitric oxide synthase 3 (NOS3; rs1799983); caveolin 1 (Cav1; rs3840634); melatonin receptor 1B (MTNR1B; rs1387153); NAD(P)H oxidase p22(phox) subunit (NADH/NADPHp22phox; rs4673); and mitochondria 5178 (MT5178; rs28357984).
|
23560644 |
2013 |
|
rs1801394
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease in individuals with polymorphisms in the genes: methionine synthase (MTR; rs1805087); methionine-synthase reductase (MTRR; rs1801394); nitric oxide synthase 3 (NOS3; rs1799983); caveolin 1 (Cav1; rs3840634); melatonin receptor 1B (MTNR1B; rs1387153); NAD(P)H oxidase p22(phox) subunit (NADH/NADPHp22phox; rs4673); and mitochondria 5178 (MT5178; rs28357984).
|
23560644 |
2013 |
|
rs2075575
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the associations between genetic polymorphisms in aquaporin 4 (AQP4, rs2075575), aquaporin 5 (AQP5, rs3736309), and estrogen receptor α (ERα1, rs2234693; ERα2, rs9340799) and susceptibility to Ménière's disease or SSNHL.
|
23352976 |
2013 |
|
rs2234693
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the associations between genetic polymorphisms in aquaporin 4 (AQP4, rs2075575), aquaporin 5 (AQP5, rs3736309), and estrogen receptor α (ERα1, rs2234693; ERα2, rs9340799) and susceptibility to Ménière's disease or SSNHL.
|
23352976 |
2013 |
|
rs28357984
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease in individuals with polymorphisms in the genes: methionine synthase (MTR; rs1805087); methionine-synthase reductase (MTRR; rs1801394); nitric oxide synthase 3 (NOS3; rs1799983); caveolin 1 (Cav1; rs3840634); melatonin receptor 1B (MTNR1B; rs1387153); NAD(P)H oxidase p22(phox) subunit (NADH/NADPHp22phox; rs4673); and mitochondria 5178 (MT5178; rs28357984).
|
23560644 |
2013 |
|
rs3736309
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the associations between genetic polymorphisms in aquaporin 4 (AQP4, rs2075575), aquaporin 5 (AQP5, rs3736309), and estrogen receptor α (ERα1, rs2234693; ERα2, rs9340799) and susceptibility to Ménière's disease or SSNHL.
|
23352976 |
2013 |
|
rs3840634
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease in individuals with polymorphisms in the genes: methionine synthase (MTR; rs1805087); methionine-synthase reductase (MTRR; rs1801394); nitric oxide synthase 3 (NOS3; rs1799983); caveolin 1 (Cav1; rs3840634); melatonin receptor 1B (MTNR1B; rs1387153); NAD(P)H oxidase p22(phox) subunit (NADH/NADPHp22phox; rs4673); and mitochondria 5178 (MT5178; rs28357984).
|
23560644 |
2013 |
|
rs4673
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease in individuals with polymorphisms in the genes: methionine synthase (MTR; rs1805087); methionine-synthase reductase (MTRR; rs1801394); nitric oxide synthase 3 (NOS3; rs1799983); caveolin 1 (Cav1; rs3840634); melatonin receptor 1B (MTNR1B; rs1387153); NAD(P)H oxidase p22(phox) subunit (NADH/NADPHp22phox; rs4673); and mitochondria 5178 (MT5178; rs28357984).
|
23560644 |
2013 |
|
rs5370
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to investigate the association between the Lys198Asn (G/T) polymorphism (rs5370) of the endothelin-1 gene and sudden sensorineural hearing loss (SSNHL).
|
23832707 |
2013 |
|
rs9340799
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the associations between genetic polymorphisms in aquaporin 4 (AQP4, rs2075575), aquaporin 5 (AQP5, rs3736309), and estrogen receptor α (ERα1, rs2234693; ERα2, rs9340799) and susceptibility to Ménière's disease or SSNHL.
|
23352976 |
2013 |
|
rs1050450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple logistic regression was used to calculate odds ratios for SSNHL and Ménière's disease in individuals with polymorphisms in the genes glutathione peroxidase 1 (GPX1) (Pro198Leu, rs1050450), paraoxonase 1 (PON1) (Gln192Arg, rs662; and Met55Leu, rs854560), PON2 (Ser311Cys, rs7493), and superoxide dismutase 2 (SOD2) (Val16Ala, rs4880), with adjustment for age and gender.
|
22877234 |
2012 |
|
rs1061170
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conclude that CFH Y402H polymorphism and SSNHL risk are significantly related, and that diabetic CFH Y402H minor allele carriers may be susceptible to SSNHL.
|
22426290 |
2012 |
|
rs1264525329
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple logistic regression was used to calculate odds ratios for SSNHL and Ménière's disease in individuals with polymorphisms in the genes glutathione peroxidase 1 (GPX1) (Pro198Leu, rs1050450), paraoxonase 1 (PON1) (Gln192Arg, rs662; and Met55Leu, rs854560), PON2 (Ser311Cys, rs7493), and superoxide dismutase 2 (SOD2) (Val16Ala, rs4880), with adjustment for age and gender.
|
22877234 |
2012 |
|
rs2075800
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The T allele of SNP rs2075800 was associated with SSNHL under the dominant model (p = 0.019; odds ratio 0.59).
|
22922572 |
2012 |