|
rs1217691063
|
|
|
0.060 |
GeneticVariation |
BEFREE |
MTHFR C677T and ApoE gene variant may be associated with sudden sensorineural hearing loss in an Iranian population.
|
30477909 |
2019 |
|
rs1217691063
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The present meta-analysis suggests that MTHFR gene C677T polymorphism is significantly associated with increased risk of SSNHL disease in European populations, but no statistically significant association was found between the MTHFR C677T gene mutation and SSNHL in Asian.
|
25012704 |
2015 |
|
rs1217691063
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We found a statistically significant higher frequency of hyperhomocysteinemia in the SSHL group compared with controls, and that this was also associated with the presence of homozygosity for the MTHFR C677T mutation.
|
20798492 |
2011 |
|
rs1217691063
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Our results suggest that the T allele of MTHFR C677T could be associated with susceptibility to SSNHL, and even imply that this mutation could be a risk factor that is independent of blood folic acid and homocysteine.
|
20213658 |
2010 |
|
rs1217691063
|
|
|
0.060 |
GeneticVariation |
BEFREE |
No statistically significant association was found between the methylenetetrahydrofolate reductase C677T gene mutation and sudden sensorineural hearing loss.
|
20492738 |
2010 |
|
rs1217691063
|
|
|
0.060 |
GeneticVariation |
BEFREE |
According to our data, factor V G1691A, prothrombin G20210A, and MTHFR C677T variants should be not considered risk factors for SSNHL.
|
16572609 |
2006 |
|
rs1799983
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our findings showed a significant association between the eNOS gene Glu298Asp polymorphism and SSNHL in the Iranian population; and "TT" genotype might be considered as a risk factor for SSNHL.
|
30354859 |
2018 |
|
rs1799983
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease in individuals with polymorphisms in the genes: methionine synthase (MTR; rs1805087); methionine-synthase reductase (MTRR; rs1801394); nitric oxide synthase 3 (NOS3; rs1799983); caveolin 1 (Cav1; rs3840634); melatonin receptor 1B (MTNR1B; rs1387153); NAD(P)H oxidase p22(phox) subunit (NADH/NADPHp22phox; rs4673); and mitochondria 5178 (MT5178; rs28357984).
|
23560644 |
2013 |
|
rs1805087
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease in individuals with polymorphisms in the genes: methionine synthase (MTR; rs1805087); methionine-synthase reductase (MTRR; rs1801394); nitric oxide synthase 3 (NOS3; rs1799983); caveolin 1 (Cav1; rs3840634); melatonin receptor 1B (MTNR1B; rs1387153); NAD(P)H oxidase p22(phox) subunit (NADH/NADPHp22phox; rs4673); and mitochondria 5178 (MT5178; rs28357984).
|
23560644 |
2013 |
|
rs751377893
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the factors V Leiden G1691A and prothrombin G20210A do not seem to play any role in Taiwanese patients with SSHL.
|
21170721 |
2011 |
|
rs899127658
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the factors V Leiden G1691A and prothrombin G20210A do not seem to play any role in Taiwanese patients with SSHL.
|
21170721 |
2011 |
|
rs1805087
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The allelic frequency of the G allele of the MTR A2756G polymorphism among SSNHL patients (12.5%) was also significantly higher than in the control group (5%) (p = 0.033).
|
16778415 |
2006 |
|
rs751377893
|
|
|
0.020 |
GeneticVariation |
BEFREE |
According to our data, factor V G1691A, prothrombin G20210A, and MTHFR C677T variants should be not considered risk factors for SSNHL.
|
16572609 |
2006 |
|
rs899127658
|
|
|
0.020 |
GeneticVariation |
BEFREE |
According to our data, factor V G1691A, prothrombin G20210A, and MTHFR C677T variants should be not considered risk factors for SSNHL.
|
16572609 |
2006 |
|
rs5498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, we propose that the combination of IL-6 -572C/G and ICAM-1 K469E polymorphisms have a synergistic effect on the onset of SSNHL.
|
29695657 |
2018 |
|
rs3805435
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As the result, the AG genotype of rs3805435 had an adjusted odds ratio (OR) of 0.54 (95% confidence interval = 0.37-0.79, p = 0.001) compared with the AA genotype in the SSNHL cases.
|
28738977 |
2017 |
|
rs10955255
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GRHL2 genetic polymorphisms, rs611419 and rs10955255, have a protective role against SSHL and reduce the risk of SSHL.
|
26847018 |
2016 |
|
rs611419
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Combined genotypes of rs611419, rs10955255 and rs6989650 in the GRHL2 gene are also associated with a reduced risk of SSHL (P=0.035).
|
26847018 |
2016 |
|
rs6989650
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Combined genotypes of rs611419, rs10955255 and rs6989650 in the GRHL2 gene are also associated with a reduced risk of SSHL (P=0.035).
|
26847018 |
2016 |
|
rs702553
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The TT genotype of rs702553</span> exhibited an adjusted odds ratio (OR</span>) of 3.83 (95 % confidence interval = 1.46-11.18) (p = 0.006) in female SSNHL.
|
26521189 |
2016 |
|
rs10489678
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, no significant differences were detected in either the genotype or allele frequencies of the other two SNPs, rs945635 and rs10489678, between the SSNHL and control groups.
|
26051414 |
2015 |
|
rs3761959
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results revealed a significant association between three SNPs-rs7528684, rs3761959, and rs7522061-and SSNHL in the studied Chinese Han population.
|
26051414 |
2015 |
|
rs7522061
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results revealed a significant association between three SNPs-rs7528684, rs3761959, and rs7522061-and SSNHL in the studied Chinese Han population.
|
26051414 |
2015 |
|
rs7528684
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five single-nucleotide polymorphisms (SNPs) in FCRL3-rs945635, rs3761959, rs7522061, rs10489678, and rs7528684-were genotyped in 630 patients with SSNHL and 600 healthy controls by using a PCR-restriction fragment length polymorphism assay.
|
26051414 |
2015 |
|
rs755622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to explore the association between the MIF (-173 G/C) polymorphism (rs755622) and SSNHL in an Iranian population.
|
26426302 |
2015 |