Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6313
rs6313
0.030 GeneticVariation BEFREE The Association between 5HT2A T102C and Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease: A Meta-Analysis. 29349076

2017

dbSNP: rs6313
rs6313
0.030 GeneticVariation BEFREE This study suggests a mechanism for the generation of different neuropsychiatric symptoms in AD from a single nucleotide polymorphism with reduced receptor binding in T102C 5-HT2A receptor gene homozygotes correlating with susceptibility to depressive symptoms, whereas the relative preservation of receptor binding in heterozygotes with AD correlating with susceptibility to hallucinations. 17481814

2007

dbSNP: rs6313
rs6313
0.030 GeneticVariation BEFREE 5-HT2A T102C receptor polymorphism and neuropsychiatric symptoms in Alzheimer's disease. 15211529

2004

dbSNP: rs6265
rs6265
0.020 GeneticVariation BEFREE Thus, the BDNF Val66Met polymorphism exerts an increase in glutamatergic transmission but impairs synaptic plasticity in the dorsal striatum, which might play a role in its effect on neuropsychiatric symptoms. 27378336

2017

dbSNP: rs759834365
rs759834365
0.020 GeneticVariation BEFREE Thus, the BDNF Val66Met polymorphism exerts an increase in glutamatergic transmission but impairs synaptic plasticity in the dorsal striatum, which might play a role in its effect on neuropsychiatric symptoms. 27378336

2017

dbSNP: rs6265
rs6265
0.020 GeneticVariation BEFREE In the present study, we examined whether neuropsychiatric symptoms were correlated with plasma brain-derived neurotrophic factor (BDNF) levels as a state marker or were associated with the BDNF polymorphism Val66Met in patients with amnestic mild cognitive impairment (A-MCI) or Alzheimer disease (AD). 24253237

2014

dbSNP: rs759834365
rs759834365
0.020 GeneticVariation BEFREE In the present study, we examined whether neuropsychiatric symptoms were correlated with plasma brain-derived neurotrophic factor (BDNF) levels as a state marker or were associated with the BDNF polymorphism Val66Met in patients with amnestic mild cognitive impairment (A-MCI) or Alzheimer disease (AD). 24253237

2014

dbSNP: rs78029637
rs78029637
0.010 GeneticVariation BEFREE The overall benefit of DBS in SNCA, GBA and LRRK2 p.T2031S mutations may be compromised due to rapid progression of cognitive and neuropsychiatric symptoms. 30659355

2020

dbSNP: rs7136446
rs7136446
0.010 GeneticVariation BEFREE Patients carrying minor alleles of rs7136446 and rs972936 showed more dizziness and multiple neuropsychiatric symptoms after brain injury. 31787098

2019

dbSNP: rs972936
rs972936
0.010 GeneticVariation BEFREE Patients carrying minor alleles of rs7136446 and rs972936 showed more dizziness and multiple neuropsychiatric symptoms after brain injury. 31787098

2019

dbSNP: rs56164415
rs56164415
0.010 GeneticVariation BEFREE The other frequently studied <i>BDNF</i> polymorphism, C270T (rs56164415), has been associated with the development of different neuropsychiatric symptoms/disorders. 30542302

2018

dbSNP: rs4680
rs4680
0.010 GeneticVariation BEFREE These findings support the hypothesis of a broad effect of the Val158Met polymorphism in the COMT gene on several dimensions of behavior and neuropsychiatric symptoms. 28235603

2017

dbSNP: rs28934908
rs28934908
0.010 GeneticVariation BEFREE Adolescent onset cognitive regression and neuropsychiatric symptoms associated with the A140V MECP2 mutation. 24328834

2014