Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913500
rs121913500
IDH1
0.050 GeneticVariation BEFREE The histopathologic examination confirmed a leptomeningeal spread of a K27M-mutated anaplastic astrocytoma (WHO° III) without R132H-IDH1 mutation. 29066318

2018
dbSNP: rs121913500
rs121913500
IDH1
0.050 GeneticVariation BEFREE Mutated IDH1 R132H protein was expressed in 2 GBM from adult patients with previous supratentorial anaplastic astrocytoma. 30203362

2018
dbSNP: rs121913500
rs121913500
IDH1
0.050 GeneticVariation BEFREE The R132H mutation in IDH1 was found in 60.5% (23/38) of patients in the AA cohort (Groups 2 and 4) and 20.0% (13/65) of patients from our GBM cohort (Groups 3 and 5), whereas all patients with ODG (Group 1) had a mutation either in IDH1 (n = 62) or IDH2 (n = 3). 28851427

2017
dbSNP: rs121913500
rs121913500
IDH1
0.050 GeneticVariation BEFREE We describe a patient who underwent surgical resection, followed by adjuvant radiation and temozolomide of a World Health Organization (WHO) III anaplastic astrocytoma in the right temporal lobe, exhibiting an IDH1 (R132H) mutation. 26911558

2016
dbSNP: rs121913500
rs121913500
IDH1
0.050 GeneticVariation BEFREE We show that expression levels of many proteins are altered in IDH1(R132H) mutant anaplastic astrocytoma. 24473683

2014
dbSNP: rs118101777
rs118101777
IDH2
0.020 GeneticVariation BEFREE The R132H mutation in IDH1 was found in 60.5% (23/38) of patients in the AA cohort (Groups 2 and 4) and 20.0% (13/65) of patients from our GBM cohort (Groups 3 and 5), whereas all patients with ODG (Group 1) had a mutation either in IDH1 (n = 62) or IDH2 (n = 3). 28851427

2017
dbSNP: rs118101777
rs118101777
IDH2
0.020 GeneticVariation BEFREE We describe a patient who underwent surgical resection, followed by adjuvant radiation and temozolomide of a World Health Organization (WHO) III anaplastic astrocytoma in the right temporal lobe, exhibiting an IDH1 (R132H) mutation. 26911558

2016
dbSNP: rs1415342243
rs1415342243
H3C6
0.010 GeneticVariation BEFREE Mutated IDH1 R132H protein was expressed in 2 GBM from adult patients with previous supratentorial anaplastic astrocytoma. 30203362

2018
dbSNP: rs55819519
rs55819519
TP53
0.010 GeneticVariation BEFREE Mutated IDH1 R132H protein was expressed in 2 GBM from adult patients with previous supratentorial anaplastic astrocytoma. 30203362

2018
dbSNP: rs760090729
rs760090729
H3C10
0.010 GeneticVariation BEFREE Mutated IDH1 R132H protein was expressed in 2 GBM from adult patients with previous supratentorial anaplastic astrocytoma. 30203362

2018
dbSNP: rs866960721
rs866960721
H3C4
0.010 GeneticVariation BEFREE Mutated IDH1 R132H protein was expressed in 2 GBM from adult patients with previous supratentorial anaplastic astrocytoma. 30203362

2018
dbSNP: rs1412829
rs1412829
CDKN2B-AS1
0.010 GeneticVariation BEFREE Wrensch and colleagues provided further evidence to 2 risk loci (CDKN2B rs1412829 and RTEL1 rs6010620) for GBM and anaplastic astrocytoma. 20212223

2010
dbSNP: rs6010620
rs6010620
RTEL1 ; RTEL1-TNFRSF6B
0.010 GeneticVariation BEFREE Wrensch and colleagues provided further evidence to 2 risk loci (CDKN2B rs1412829 and RTEL1 rs6010620) for GBM and anaplastic astrocytoma. 20212223

2010