|
rs113488022
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The recent surge in next generation sequencing (NGS) technology has shed more light on the genetic landscape of SBCLs through characterization of numerous driver mutations including SF3B1 and NOTCH1 in CLL, ATM and CCND1 in MCL, KMT2D and EPHA7 in FL, MYD88 (L265P) in LPL, KLF2 and NOTCH2 in splenic MZL (SMZL) and BRAF (V600E) in HCL.
|
27121112 |
2016 |
|
rs121913377
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The recent surge in next generation sequencing (NGS) technology has shed more light on the genetic landscape of SBCLs through characterization of numerous driver mutations including SF3B1 and NOTCH1 in CLL, ATM and CCND1 in MCL, KMT2D and EPHA7 in FL, MYD88 (L265P) in LPL, KLF2 and NOTCH2 in splenic MZL (SMZL) and BRAF (V600E) in HCL.
|
27121112 |
2016 |
|
rs113488022
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The performance of the BRAF V600E-specific VE1 antibody was compared with that of allele-specific polymerase chain reaction (PCR) in 22 formalin-fixed, paraffin-embedded (FFPE) specimens with HCL involvement, along with nine splenic marginal zone lymphomas (SMZLs), 10 follicular lymphomas (FLs), 10 mantle cell lymphomas (MCLs), and 10 chronic lymphocytic leukemia/small lymphocytic lymphomas (CLL/SLLs).
|
25511147 |
2015 |
|
rs121913377
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The performance of the BRAF V600E-specific VE1 antibody was compared with that of allele-specific polymerase chain reaction (PCR) in 22 formalin-fixed, paraffin-embedded (FFPE) specimens with HCL involvement, along with nine splenic marginal zone lymphomas (SMZLs), 10 follicular lymphomas (FLs), 10 mantle cell lymphomas (MCLs), and 10 chronic lymphocytic leukemia/small lymphocytic lymphomas (CLL/SLLs).
|
25511147 |
2015 |
|
rs6083471
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNPs rs80351309 and rs6083471 show a statistically significant association with MCL injury.
|
28482362 |
2017 |
|
rs80351309
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNPs rs803</span>51309 and rs6083471 show a statistically significant association with MCL injury.
|
28482362 |
2017 |
|
rs1392080411
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The recent surge in next generation sequencing (NGS) technology has shed more light on the genetic landscape of SBCLs through characterization of numerous driver mutations including SF3B1 and NOTCH1 in CLL, ATM and CCND1 in MCL, KMT2D and EPHA7 in FL, MYD88 (L265P) in LPL, KLF2 and NOTCH2 in splenic MZL (SMZL) and BRAF (V600E) in HCL.
|
27121112 |
2016 |
|
rs387907272
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The recent surge in next generation sequencing (NGS) technology has shed more light on the genetic landscape of SBCLs through characterization of numerous driver mutations including SF3B1 and NOTCH1 in CLL, ATM and CCND1 in MCL, KMT2D and EPHA7 in FL, MYD88 (L265P) in LPL, KLF2 and NOTCH2 in splenic MZL (SMZL) and BRAF (V600E) in HCL.
|
27121112 |
2016 |
|
rs1057519825
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma.
|
25082755 |
2014 |
|
rs1057519826
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma.
|
25082755 |
2014 |
|
rs2509049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correction for multiple testing, significant associations were present for mantle cell lymphoma (p=0.007 for rs604714) and all B-cell lymphomas (p=0.046 for rs2509049).
|
24069324 |
2013 |
|
rs604714
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correction for multiple testing, significant associations were present for mantle cell lymphoma (p=0.007 for rs604714) and all B-cell lymphomas (p=0.046 for rs2509049).
|
24069324 |
2013 |
|
rs11547328
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We propose that similarly to typical human MCL and its blastoid or cyclin-D1 variants that correspond to the same genetic entity, MCL-like lymphomas of c-myc-3'RR/ p53+/- mice and c-myc-3'RR/Cdk4(R24C) mice represent a spectrum of the same entity.
|
22592113 |
2012 |
|
rs563378859
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We propose that similarly to typical human MCL and its blastoid or cyclin-D1 variants that correspond to the same genetic entity, MCL-like lymphomas of c-myc-3'RR/ p53+/- mice and c-myc-3'RR/Cdk4(R24C) mice represent a spectrum of the same entity.
|
22592113 |
2012 |
|
rs121913507
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In most patients with systemic mastocytosis (SM), including aggressive SM (ASM) and mast cell (MC) leukemia (MCL), neoplastic cells express the oncogenic KIT mutation D816V, which confers resistance to imatinib.
|
20553795 |
2010 |
|
rs121913682
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In most patients with systemic mastocytosis (SM), including aggressive SM (ASM) and mast cell (MC) leukemia (MCL), neoplastic cells express the oncogenic KIT mutation D816V, which confers resistance to imatinib.
|
20553795 |
2010 |
|
rs1800629
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TNF rs1800629 was associated with risk of NHL (OR 1.53, 95% confidence interval, CI, 1.06-2.19 for minor allele homozygosity), T-cell lymphoma (OR 2.54, CI 1.27-5.09) and mantle cell lymphoma (OR 2.84, CI 1.38-5.87).
|
20087644 |
2010 |
|
rs1800890
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL10 rs1800890 was associated with risk of diffuse large B-cell lymphoma (OR 1.41, CI 1.08-1.85 for minor allele homozygosity) and mantle cell lymphoma (OR 1.77, CI 1.04-3.00).
|
20087644 |
2010 |
|
rs20576
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study we analyzed the complete coding region of TNFRSF10A and TNFRSF10B in a series of 32 MCL and 101 CLL samples and detected a single nucleotide polymorphism (SNP) in TNFRSF10A (A683C) with tumor specific allele distribution.
|
16217763 |
2006 |
|
rs17879961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A heterozygous Ile157Thr substitution, also present in the germ line of the patient, was detected in a blastoid mantle cell lymphoma (MCL).
|
12393693 |
2002 |
|
rs760043106
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A heterozygous Ile157Thr substitution, also present in the germ line of the patient, was detected in a blastoid mantle cell lymphoma (MCL).
|
12393693 |
2002 |