Disease: Metabolic Syndrome X
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1000283
HSD11B1 ; HSD11B1-AS1
0.925 0.080 1 209721316 intron variant G/A snv 0.18 2
rs1137101
LEPR
0.554 0.760 1 65592830 missense variant A/G snv 0.51 0.50 77
rs12086634
HSD11B1-AS1 ; HSD11B1
0.827 0.280 1 209706914 intron variant T/G snv 0.21 0.20 6
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs17368528
H6PD
0.827 0.400 1 9264154 missense variant C/A;T snv 0.12 8.9E-02 5
rs1801131
MTHFR
0.535 0.840 1 11794419 missense variant T/G snv 0.29 0.26 93
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27 174
rs1805094
LEPR
0.716 0.440 1 65610269 missense variant G/C;T snv 0.16; 4.0E-06 16
rs2228145
IL6R
0.602 0.720 1 154454494 missense variant A/C;T snv 0.38; 1.2E-05 57
rs2516839
USF1
0.732 0.320 1 161043331 5 prime UTR variant C/T snv 0.49 14
rs324420
FAAH
0.637 0.440 1 46405089 missense variant C/A snv 0.24 0.26 48
rs340874
PROX1 ; PROX1-AS1
0.882 0.080 1 213985913 non coding transcript exon variant T/C snv 0.40 7
rs3737787
TSTD1 ; USF1
0.763 0.280 1 161039733 3 prime UTR variant G/A snv 0.21 11
rs397507444
MTHFR
0.405 0.880 1 11794407 missense variant T/G snv 306
rs4641
LMNA
0.851 0.120 1 156137743 splice region variant C/T snv 0.26 0.21 6
rs4762
AGT
0.637 0.440 1 230710231 missense variant G/A snv 0.12 0.11 35
rs5068
NPPA ; NPPA-AS1 ; CLCN6
0.776 0.160 1 11845917 3 prime UTR variant A/G;T snv 13
rs6688832
H6PD
0.752 0.440 1 9263851 missense variant G/A;C snv 0.28; 1.2E-04 10
rs699
AGT
0.501 0.800 1 230710048 missense variant A/G snv 0.55 0.58 134
rs726344
FNDC5
0.882 0.120 1 32867503 intron variant G/A snv 0.16 3
rs80356814
LMNA
0.732 0.320 1 156138697 synonymous variant C/T snv 8.0E-06 15
rs846910
HSD11B1 ; HSD11B1-AS1
0.882 0.160 1 209701909 intron variant A/G snv 0.95 6
rs1260326
GCKR
0.645 0.600 2 27508073 missense variant T/C;G snv 0.63; 4.0E-06 0.68 81
rs1801276
IRS1
0.882 0.160 2 226797205 missense variant C/G snv 1.4E-02 1.3E-02 3
rs1801278
IRS1
0.637 0.560 2 226795828 missense variant C/G;T snv 4.0E-06; 5.2E-02 38