Disease: Metabolic Syndrome X
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs146052672
HMGA1
0.851 0.160 6 34242693 intron variant -/C delins 5
rs5186
AGTR1
0.630 0.560 3 148742201 3 prime UTR variant A/C snv 0.23 0.21 38
rs2943634 0.763 0.200 2 226203364 intergenic variant A/C;G snv 15
rs2228145
IL6R
0.602 0.720 1 154454494 missense variant A/C;T snv 0.38; 1.2E-05 57
rs2237895
KCNQ1
0.790 0.240 11 2835964 intron variant A/C;T snv 10
rs7041
GC
0.576 0.800 4 71752617 missense variant A/C;T snv 0.52; 4.0E-06 64
rs10010131
WFS1
0.827 0.120 4 6291188 intron variant A/G snv 0.66 0.63 7
rs10247649
PDK4
0.925 0.080 7 95586935 non coding transcript exon variant A/G snv 0.43 2
rs1051295
KCNB1 ; LOC105372649
0.925 0.080 20 49372368 3 prime UTR variant A/G snv 0.22 3
rs1052717
SREBF2
0.925 0.080 22 41885425 intron variant A/G snv 0.62 3
rs10738760 0.807 0.320 9 2691186 regulatory region variant A/G snv 0.56 7
rs10757278
CDKN2B-AS1
0.620 0.520 9 22124478 intron variant A/G snv 0.40 44
rs10938397 0.851 0.200 4 45180510 intergenic variant A/G snv 0.37 19
rs11063069
CCND2-AS1
0.925 0.080 12 4265207 intron variant A/G snv 0.20 2
rs1137101
LEPR
0.554 0.760 1 65592830 missense variant A/G snv 0.51 0.50 77
rs11708067
ADCY5
0.882 0.080 3 123346931 intron variant A/G snv 0.19 9
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs1800625
AGER ; PBX2
0.641 0.680 6 32184665 upstream gene variant A/G snv 0.15 39
rs1800797
IL6 ; IL6-AS1 ; STEAP1B
0.605 0.800 7 22726602 non coding transcript exon variant A/G snv 0.72 43
rs1801260
CLOCK ; TMEM165
0.695 0.280 4 55435202 3 prime UTR variant A/G snv 0.25 28
rs1801394
FASTKD3 ; MTRR
0.531 0.840 5 7870860 missense variant A/G snv 0.47 0.45 101
rs2267443
SREBF2
0.882 0.120 22 41891450 intron variant A/G snv 0.67 5
rs2383207
CDKN2B-AS1
0.695 0.280 9 22115960 intron variant A/G snv 0.64 22
rs268
LPL
0.637 0.480 8 19956018 missense variant A/G snv 1.3E-02 1.3E-02 41
rs4757268
PDE3B
0.827 0.120 11 14789216 synonymous variant A/G snv 0.63 0.64 6