PON1, paraoxonase 1, 5444

N. diseases: 496; N. variants: 29
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0741923
Disease: cardiac event
cardiac event 		phenotype Disease or Syndrome 82 18 0.040 None 1.000 4 2014 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		phenotype Neoplastic Process 6626 169 0.040 None 1.000 4 2009 2018
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		phenotype Disease or Syndrome 716 25 0.030 None 1.000 3 2008 2017
CUI: C3272265
Disease: Three Vessel Coronary Disease
Three Vessel Coronary Disease 		disease Disease or Syndrome 11 2 0.030 None 1.000 3 2003 2012
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		disease Neoplastic Process 3669 502 0.030 None 1.000 3 2 2005 2019
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor 		phenotype Neoplastic Process 735 33 0.020 None 1.000 2 2018 2018
CUI: C0687132
Disease: heavy drinking
heavy drinking 		disease Mental or Behavioral Dysfunction 57 7 0.310 None 1.000 2 2003 2007
CUI: C0877008
Disease: Enzyme inhibition disorder
Enzyme inhibition disorder 		phenotype Disease or Syndrome 171 1 0.020 None 1.000 2 2017 2019
CUI: C1504375
Disease: Diabetic macroangiopathy
Diabetic macroangiopathy 		disease Disease or Syndrome 9 2 0.020 None 1.000 2 2 2018 2018
CUI: C2257843
Disease: paraoxonase activity
paraoxonase activity 		phenotype Molecular Function 1 3 0.100 None 1.000 2 3 2012 2013
CUI: C4237343
Disease: Overweight or obesity
Overweight or obesity 		phenotype Disease or Syndrome 35 17 0.020 None 1.000 2 2 2014 2019
CUI: C0201899
Disease: Aspartate aminotransferase measurement
Aspartate aminotransferase measurement 		phenotype Laboratory Procedure 57 76 0.100 None 1.000 1 2 2017 2017
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement 		phenotype Laboratory Procedure 563 1418 0.100 None 1.000 1 1 2012 2012
CUI: C0220810
Disease: Congenital defects
Congenital defects 		group Congenital Abnormality 126 6 0.010 None 1.000 1 1998 1998
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders 		group Mental or Behavioral Dysfunction 360 56 0.010 None 1.000 1 2017 2017
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		phenotype Laboratory Procedure 433 3282 0.100 None 1.000 1 1 2013 2013
CUI: C0857256
Disease: Unwell
Unwell 		phenotype Sign or Symptom 1 0.010 None 1.000 1 2011 2011
CUI: C0948379
Disease: Impaired insulin secretion
Impaired insulin secretion 		disease Disease or Syndrome 88 14 0.010 None 1.000 1 2018 2018
CUI: C1096293
Disease: Macroangiopathy
Macroangiopathy 		disease Disease or Syndrome 31 6 0.010 None < 0.001 1 1 2018 2018
CUI: C1337013
Disease: Differentiated Thyroid Gland Carcinoma
Differentiated Thyroid Gland Carcinoma 		disease Neoplastic Process 245 80 0.010 None 1.000 1 2018 2018
CUI: C1392046
Disease: Cardiovascular insufficiency
Cardiovascular insufficiency 		disease Disease or Syndrome 1 0.010 None 1.000 1 2019 2019
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		phenotype Laboratory Procedure 486 1243 0.100 None 1.000 1 1 2012 2012
CUI: C1561826
Disease: Overweight and obesity
Overweight and obesity 		disease Disease or Syndrome 81 29 0.010 None 1.000 1 2019 2019
CUI: C2609253
Disease: Macrovascular disease
Macrovascular disease 		disease Disease or Syndrome 23 1 0.010 None 1.000 1 2003 2003
CUI: C2938924
Disease: Oestrogen receptor positive breast cancer
Oestrogen receptor positive breast cancer 		disease Neoplastic Process 510 58 0.010 None 1.000 1 2011 2011