PRNP, prion protein, 5621

N. diseases: 426; N. variants: 47
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease Pathological Conditions, Signs and Symptoms Acquired Abnormality 249 21 0.200 None 0.900 10 1 1991 2020
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		disease Neoplastic Process 3669 502 0.100 None 1.000 10 1 2008 2019
CUI: C0338451
Disease: Frontotemporal dementia
Frontotemporal dementia 		disease Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders Disease or Syndrome 320 215 0.090 None 0.778 9 3 2011 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		disease Neoplasms; Skin and Connective Tissue Diseases Neoplastic Process 6776 2793 0.090 None 1.000 9 1999 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		disease Digestive System Diseases; Neoplasms Neoplastic Process 3806 615 0.370 None 1.000 8 2005 2018
CUI: C4303527
Disease: Variably protease sensitive prionopathy
Variably protease sensitive prionopathy 		disease Infections; Nervous System Diseases Disease or Syndrome 1 1 0.080 None 1.000 8 1 2011 2019
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		disease Neoplasms; Skin and Connective Tissue Diseases Neoplastic Process 6941 3417 0.070 None 1.000 7 1999 2019
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		disease Neoplasms Neoplastic Process 3177 281 0.070 None 1.000 7 2008 2019
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		disease Nervous System Diseases; Mental Disorders Disease or Syndrome 213 83 0.070 None 0.857 7 2 2011 2018
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		disease Digestive System Diseases; Neoplasms Neoplastic Process 3720 652 0.070 None 1.000 7 2005 2018
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		disease Neoplasms Neoplastic Process 2528 98 0.060 None 1.000 6 2008 2019
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		disease Neoplasms Neoplastic Process 2527 98 0.060 None 1.000 6 2008 2019
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		disease Neoplasms Neoplastic Process 3197 186 0.060 None 1.000 6 2008 2019
CUI: C0008479
Disease: Chondrosarcoma
Chondrosarcoma 		disease Neoplasms Neoplastic Process 385 8 0.050 None 1.000 5 2009 2019
CUI: C0014544
Disease: Epilepsy
Epilepsy 		disease Nervous System Diseases Disease or Syndrome 1215 339 0.050 None 1.000 5 2002 2014
CUI: C0232197
Disease: Fibrillation
Fibrillation 		disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases Disease or Syndrome 118 8 0.050 None 1.000 5 2018 2019
CUI: C0751645
Disease: Human Transmissible Spongiform Encephalopathies, Inherited
Human Transmissible Spongiform Encephalopathies, Inherited 		disease Infections; Nervous System Diseases Disease or Syndrome 2 0.310 None 1.000 5 1998 2007
CUI: C1847651
Disease: Rapidly progressive dementia
Rapidly progressive dementia 		disease Nervous System Diseases; Mental Disorders Mental or Behavioral Dysfunction 9 4 0.050 None 1.000 5 2 2001 2019
CUI: C4275003
Disease: Familial Creutzfeldt-Jakob
Familial Creutzfeldt-Jakob 		disease Infections; Nervous System Diseases; Mental Disorders Disease or Syndrome 1 1 0.050 None 1.000 5 1 1991 2014
CUI: C4698644
Disease: Atypical scrapie
Atypical scrapie 		disease Disease or Syndrome 2 0.050 None 1.000 5 2008 2018
CUI: C0012546
Disease: Diphtheria
Diphtheria 		disease Infections Disease or Syndrome 147 0.040 None 1.000 4 2007 2019
CUI: C0014556
Disease: Epilepsy, Temporal Lobe
Epilepsy, Temporal Lobe 		disease Nervous System Diseases Disease or Syndrome 354 33 0.040 None 0.750 4 2 2006 2014
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		disease Digestive System Diseases; Infections Disease or Syndrome 1449 519 0.040 None 1.000 4 2007 2019
CUI: C0021400
Disease: Influenza
Influenza 		disease Infections; Respiratory Tract Diseases Disease or Syndrome 858 17 0.040 None 1.000 4 2007 2020
CUI: C0032027
Disease: Pityriasis Rubra Pilaris
Pityriasis Rubra Pilaris 		disease Skin and Connective Tissue Diseases Disease or Syndrome 32 2 0.040 None 1.000 4 1993 2019