NAT2, N-acetyltransferase 2, 10

N. diseases: 311; N. variants: 10
Disease: Orofacial cleft ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3266076
Disease: Orofacial cleft
Orofacial cleft 		0.020 Biomarker disease BEFREE We investigated whether polymorphic variants of fetal acetyl-N-transferases 1 (NAT1) and 2 (NAT2) interact with maternal cigarette smoking during early pregnancy to increase the risk of delivering an infant with an orofacial cleft. 15127906 2004
CUI: C3266076
Disease: Orofacial cleft
Orofacial cleft 		0.020 Biomarker disease BEFREE No interaction between maternal NAT2 acetylator status and smoking or medication use was observed for orofacial cleft and spina bifida risk. 12397635 2002