CDH2, cadherin 2, 1000

N. diseases: 28; N. variants: 4
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.380 Biomarker phenotype CTD_human Cadmium induces N-cadherin cleavage via ERK-mediated γ-secretase activation in C6 astroglia cells. 23876460 2013
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.320 Biomarker disease CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.320 Biomarker disease CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
CUI: C0454455
Disease: Mirror movements disorder
Mirror movements disorder 		0.310 Biomarker disease GENOMICS_ENGLAND N-cadherin mediates cortical organization in the mouse brain. 17222817 2007
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability 		0.310 Biomarker group GENOMICS_ENGLAND N-cadherin mediates cortical organization in the mouse brain. 17222817 2007
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.310 Biomarker group CTD_human Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray. 16367923 2006
CUI: C0027626
Disease: Neoplasm Invasiveness
Neoplasm Invasiveness 		0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker disease CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.300 Biomarker group CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human 		0.300 Biomarker disease CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker phenotype CTD_human Cadmium induces N-cadherin cleavage via ERK-mediated γ-secretase activation in C6 astroglia cells. 23876460 2013
CUI: C0013261
Disease: Duane Retraction Syndrome
Duane Retraction Syndrome 		0.300 Biomarker disease GENOMICS_ENGLAND N-cadherin mediates cortical organization in the mouse brain. 17222817 2007
CUI: C0557874
Disease: Global developmental delay
Global developmental delay 		0.300 Biomarker disease GENOMICS_ENGLAND N-cadherin mediates cortical organization in the mouse brain. 17222817 2007
CUI: C0744356
Disease: Abnormality of the genital system
Abnormality of the genital system 		0.300 Biomarker phenotype GENOMICS_ENGLAND N-cadherin mediates cortical organization in the mouse brain. 17222817 2007
CUI: C1837249
Disease: Malformations of Cortical Development, Group II
Malformations of Cortical Development, Group II 		0.300 Biomarker disease GENOMICS_ENGLAND N-cadherin mediates cortical organization in the mouse brain. 17222817 2007
CUI: C1842581
Disease: Abnormal corpus callosum morphology
Abnormal corpus callosum morphology 		0.300 Biomarker phenotype GENOMICS_ENGLAND N-cadherin mediates cortical organization in the mouse brain. 17222817 2007
CUI: C4316870
Disease: Abnormality of the eye
Abnormality of the eye 		0.300 Biomarker phenotype GENOMICS_ENGLAND N-cadherin mediates cortical organization in the mouse brain. 17222817 2007
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.300 Biomarker disease CTD_human Methylation status of the 32 randomly selected and 16 potential tumor-related genes was analyzed in 10 primary gastric cancers, and 42 genes (ABHD9, ADFP, ALDH1A3, ANXA5, AREG, BDNF, BMP7, CAV1, CDH2, CLDN3, CTSL, EEF1A2, F2R, FADS1, FSD1, FST, FYN, GPR54, GREM1, IGFBP3, IGFBP7, IRS2, KISS1, MARK1, MLF1, MSX1, MTSS1, NT5E, PAX6, PLAGL1, PLAU, PPIC, RBP4, RORA, SCRN1, TBX3, TFAP2C, TNFSF9, ULBP2, WIF1, ZNF177 and ZNF559) were methylated in at least one primary gastric cancer. 16367923 2006
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker disease CTD_human Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray. 16367923 2006
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.300 Biomarker disease CTD_human Cardioplegia prevents ischemia-induced transcriptional alterations of cytoprotective genes in rat hearts: a DNA microarray study. 16214533 2005
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.300 Biomarker phenotype CTD_human Differential regulation of cadherins and catenins during axonal reorganization in the adult rat CNS. 12387456 2002
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.300 Biomarker disease CTD_human Neural (N-) cadherin, a synaptic adhesion molecule, is induced in hippocampal mossy fiber axonal sprouts by seizure. 12125071 2002
CUI: C0270823
Disease: Petit mal status
Petit mal status 		0.300 Biomarker disease CTD_human Neural (N-) cadherin, a synaptic adhesion molecule, is induced in hippocampal mossy fiber axonal sprouts by seizure. 12125071 2002
CUI: C0311335
Disease: Grand Mal Status Epilepticus
Grand Mal Status Epilepticus 		0.300 Biomarker disease CTD_human Neural (N-) cadherin, a synaptic adhesion molecule, is induced in hippocampal mossy fiber axonal sprouts by seizure. 12125071 2002
CUI: C0393734
Disease: Complex Partial Status Epilepticus
Complex Partial Status Epilepticus 		0.300 Biomarker disease CTD_human Neural (N-) cadherin, a synaptic adhesion molecule, is induced in hippocampal mossy fiber axonal sprouts by seizure. 12125071 2002