ABI1, abl interactor 1, 10006

N. diseases: 56; N. variants: 1
Disease: Colonic Polyps ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009376
Disease: Colonic Polyps
Colonic Polyps 		0.010 AlteredExpression phenotype BEFREE In this study, our aim was to investigate the expression of Abi1 in colonic mucosa with and without inflammation, colonic polyps, colorectal carcinomas (CRC) and metastases as well as in CRC cell lines with respect to BRAF/KRAS mutation status and to find out whether introduction of KRAS mutation or stimulation with TNFalpha enhances Abi1 protein expression in CRC cells. 22808230 2012