|
Liver carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
PITPNA-AS1 abrogates the inhibition of miR-876-5p on WNT5A to facilitate hepatocellular carcinoma progression.
|
31700026 |
2019 |
|
Liver carcinoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
HCC tissues with high miR-876-5p level showed a higher E-cadherin staining compared to cases with low miR-876-5p level.
|
29679906 |
2018 |
|
Liver carcinoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Two HCC cells were chosen to do functional assays after miR-876-5p expression was detected in cell lines by qRT-PCR.
|
29724530 |
2018 |
|
Liver carcinoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Therefore, miRNAs with dysregulated expression are potential therapeutic targets for the treatment of GBM. miRNA‑876‑5p (miR‑876‑5p) has recently been identified to be aberrantly expressed and serve an important role in hepatocellular carcinoma and lung cancer.
|
30365126 |
2019 |
|
Liver carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
MicroRNAs (miRNAs) are widely expressed in human cells and closely associated with various types of cancer, including breast cancer. miR-876-5p has been indicated to participate in the tumorigenesis of certain types of cancer, such as hepatocellular carcinoma.
|
31316633 |
2019 |
|
Malignant neoplasm of breast
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Restoration of miR-876 expression decreased breast cancer cell proliferation, migration and invasion in vitro and restricted tumor growth in vivo as well as increased cell apoptosis.
|
31239777 |
2019 |
|
Malignant neoplasm of breast
|
0.030 |
Biomarker
|
disease |
BEFREE |
FBXL19-AS1 promotes cell proliferation and inhibits cell apoptosis via miR-876-5p/FOXM1 axis in breast cancer.
|
31696201 |
2019 |
|
Malignant neoplasm of breast
|
0.030 |
Biomarker
|
disease |
BEFREE |
In summary, the results from the present study provide evidence that miR-876-5p suppresses breast cancer progression by regulating cell proliferation, migration and invasion in a TFAP2A-dependent manner.
|
31316633 |
2019 |
|
Malignant neoplasm of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
MiR-876-5p, a member of miRNA family, has been studied in lung cancer for its anti-oncogenic function.
|
29724530 |
2018 |
|
Malignant neoplasm of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
A xenograft tumour mouse model was established to address the roles of microRNA-876-5p and BMP-4 in lung cancer EMT <i>in vivo</i>.
|
29229885 |
2017 |
|
Malignant neoplasm of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
Therefore, miRNAs with dysregulated expression are potential therapeutic targets for the treatment of GBM. miRNA‑876‑5p (miR‑876‑5p) has recently been identified to be aberrantly expressed and serve an important role in hepatocellular carcinoma and lung cancer.
|
30365126 |
2019 |
|
Breast Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
In summary, the results from the present study provide evidence that miR-876-5p suppresses breast cancer progression by regulating cell proliferation, migration and invasion in a TFAP2A-dependent manner.
|
31316633 |
2019 |
|
Breast Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
FBXL19-AS1 promotes cell proliferation and inhibits cell apoptosis via miR-876-5p/FOXM1 axis in breast cancer.
|
31696201 |
2019 |
|
Breast Carcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Restoration of miR-876 expression decreased breast cancer cell proliferation, migration and invasion in vitro and restricted tumor growth in vivo as well as increased cell apoptosis.
|
31239777 |
2019 |
|
Carcinoma of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
MiR-876-5p, a member of miRNA family, has been studied in lung cancer for its anti-oncogenic function.
|
29724530 |
2018 |
|
Carcinoma of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
A xenograft tumour mouse model was established to address the roles of microRNA-876-5p and BMP-4 in lung cancer EMT <i>in vivo</i>.
|
29229885 |
2017 |
|
Carcinoma of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
Therefore, miRNAs with dysregulated expression are potential therapeutic targets for the treatment of GBM. miRNA‑876‑5p (miR‑876‑5p) has recently been identified to be aberrantly expressed and serve an important role in hepatocellular carcinoma and lung cancer.
|
30365126 |
2019 |
|
Primary malignant neoplasm of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
MiR-876-5p, a member of miRNA family, has been studied in lung cancer for its anti-oncogenic function.
|
29724530 |
2018 |
|
Primary malignant neoplasm of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
Therefore, miRNAs with dysregulated expression are potential therapeutic targets for the treatment of GBM. miRNA‑876‑5p (miR‑876‑5p) has recently been identified to be aberrantly expressed and serve an important role in hepatocellular carcinoma and lung cancer.
|
30365126 |
2019 |
|
Primary malignant neoplasm of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
A xenograft tumour mouse model was established to address the roles of microRNA-876-5p and BMP-4 in lung cancer EMT <i>in vivo</i>.
|
29229885 |
2017 |
|
Glioma
|
0.020 |
Biomarker
|
disease |
BEFREE |
We also demonstrated the inhibitory effect of miR-876-3p on tumor growth in glioma using an in vivo model.
|
31497212 |
2019 |
|
Glioma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our results conclude that HOXC-AS2/miR-876-5p/ZEB1 constitutes a positive feedback loop to regulate EMT in GBM, providing a potential therapeutic target for glioma.
|
31571911 |
2019 |
|
Malignant neoplasm of stomach
|
0.020 |
Biomarker
|
disease |
BEFREE |
Finally, rescue assay uncovered a fact that miR-876-5p suppressed GC cell viability and migration, but induced cell apoptosis via targeting WNT5A and MITF.
|
31171711 |
2019 |
|
Malignant neoplasm of stomach
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
MiR-876-3p was downregulated in GC, and its mRNA level had negative relationship with cisplatin resistance of GC.
|
30843262 |
2019 |
|
Squamous cell carcinoma of esophagus
|
0.020 |
Biomarker
|
disease |
BEFREE |
Collectively, our study provided novel evidence that ciRS-7 accelerates ESCC progression by acting as a miR-876-5p sponge to enhance MAGE-A family expression.
|
29635069 |
2018 |