HDAC6, histone deacetylase 6, 10013

N. diseases: 288; N. variants: 1
Disease: Depressive disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.310 Biomarker disease BEFREE Nonetheless, a mechanistic understanding for HDAC6 inhibitors in the treatment of depression remains elusive. 29463911 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.310 Biomarker disease PSYGENET These findings suggest that HDAC6-mediated reversible acetylation might contribute to maintain proper neuronal activity in serotonergic neurons, and also provide a new therapeutic target for depression. 22328923 2012