HDAC6, histone deacetylase 6, 10013

N. diseases: 288; N. variants: 1
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.060 AlteredExpression group BEFREE Herein, we reported that histone deacetylase 6 (HDAC6), one of class II histone deacetylases, was frequently upregulated in the CAFs of breast tumor and promotes an immunosuppressive microenvironment. 29980788 2018
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.060 Biomarker group BEFREE We previously found that in breast tumor MDA-MB-231 cells an increase of microtubule and cortactin acetylation upon inhibition of HDAC6 correlates with a decrease of matrix degradation and invasion in three-dimensional collagen I gel. 22902175 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.060 AlteredExpression group BEFREE HDAC6 is required for invadopodia activity and invasion by breast tumor cells. 20970878 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.060 Biomarker group LHGDN Role of the aggresome pathway in cancer: targeting histone deacetylase 6-dependent protein degradation. 18413721 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.060 AlteredExpression group LHGDN Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer. 15806142 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.060 AlteredExpression group LHGDN HDAC6 expression is correlated with better survival in breast cancer. 15501975 2004