BCL2L11, BCL2 like 11, 10018

N. diseases: 173; N. variants: 16
Disease: Acute lymphocytic leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia 		0.050 Biomarker disease BEFREE Glucocorticoid Resistance in Acute Lymphoblastic Leukemia: BIM Finally. 30537507 2018
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia 		0.050 GeneticVariation disease BEFREE These observations suggest that an association of a deletion polymorphism of BIM and the response to induction therapy in BCP-ALL may be clinically minimal. 28641145 2017
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia 		0.050 Biomarker disease BEFREE Hence, our results provide novel insight into the mechanism of apoptosis upon oncogene inactivation and suggest that induction of BIM-mediated apoptosis may be an important therapeutic approach for ALL. 27095570 2016
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia 		0.050 GeneticVariation disease BEFREE Accordingly, we used zinc finger nucleases to generate ALL cell lines with the BIM deletion, and confirmed the ability of the deletion to mediate GC resistance in vitro. 25090024 2014
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia 		0.050 GeneticVariation disease BEFREE We investigated Bim gene polymorphisms and their association with childhood ALL outcome, and the mechanism underlying the observed finding. 23908358 2013