BCL2L11, BCL2 like 11, 10018

N. diseases: 173; N. variants: 16
Disease: Tumor necrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333516
Disease: Tumor necrosis
Tumor necrosis 		0.010 AlteredExpression phenotype BEFREE Furthermore, in vivo xenograft studies demonstrated a 50% reduction in tumor burden (P<0.0001), a 5- to 15-fold increase in BIM expression (P < 0.0001) and a fourfold increase in tumor necrosis in Givinostat/Sorafenib-treated animals compared with mice that received single agents. 24561519 2014