Disease: Sick Sinus Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0037052
Disease: Sick Sinus Syndrome
Sick Sinus Syndrome 		0.440 AlteredExpression disease BEFREE This study is to investigate how mitochondrial oxidative stress induces HCN4 downregulation associated with in sick sinus syndrome. 31751569 2020
CUI: C0037052
Disease: Sick Sinus Syndrome
Sick Sinus Syndrome 		0.440 GeneticVariation disease BEFREE Sick sinus syndrome with HCN4 mutations shows early onset and frequent association with atrial fibrillation and left ventricular noncompaction. 28104484 2017
CUI: C0037052
Disease: Sick Sinus Syndrome
Sick Sinus Syndrome 		0.440 GeneticVariation disease BEFREE Mutations affecting the HCN4 gene are associated primarily with sick sinus syndrome. 28465117 2017
CUI: C0037052
Disease: Sick Sinus Syndrome
Sick Sinus Syndrome 		0.440 GeneticVariation disease BEFREE The HCN4 channel controls the heart rate, and its mutations predispose to inherited sick sinus syndrome and long QT syndrome associated with bradycardia. 19165230 2009
CUI: C0037052
Disease: Sick Sinus Syndrome
Sick Sinus Syndrome 		0.440 GermlineCausalMutation disease ORPHANET
CUI: C0037052
Disease: Sick Sinus Syndrome
Sick Sinus Syndrome 		0.440 Biomarker disease HPO