MIR1260B, microRNA 1260b, 100422991

N. diseases: 21; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 Biomarker disease BEFREE After the two-phase selection and validation process, we identified a miRNA panel (miR-144-3p, miR-425-5p, and miR-1260b) with high diagnostic efficiency for CRC; the panel distinguished CRC patients from controls with 93.8% sensitivity and 91.3% specificity. 30925282 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 Biomarker disease BEFREE Furthermore, it was validated that programmed cell death 4 (PDCD4) was a direct target of miR-1260b inhibitor in CRC with bioinformatics tools and a luciferase assay. 30250581 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 AlteredExpression disease BEFREE RESULTS The miR-1260b expression in CRC was significantly higher than the expression levels in the corresponding para-carcinoma tissues (P<0.001). 27399918 2016