Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Necrotizing enterocolitis in fetus OR newborn
0.040 AlteredExpression disease BEFREE Ileal expression of claudin-2, -3, -4, occludin, and ZO-1 was upregulated in NEC+HA 35 and HA 35 compared to untreated NEC and shams. 31499514 2019
Necrotizing enterocolitis in fetus OR newborn
0.040 AlteredExpression disease BEFREE The tight junction genes ZO-1, occludin, cingulin and claudin-4 were significantly down regulated in NEC. 29276042 2018
Necrotizing enterocolitis in fetus OR newborn
0.040 Biomarker disease BEFREE RNA and protein assays for occludin protein were performed for all models of NEC. 29927318 2018
Necrotizing enterocolitis in fetus OR newborn
0.040 Biomarker disease BEFREE Thus, an increase in intestinal permeability precedes NEC and is associated with internalization of claudin 4 and occludin. 23470164 2013