KLRC4-KLRK1, KLRC4-KLRK1 readthrough, 100528032

N. diseases: 246; N. variants: 5
Disease: Hepatitis B ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.050 PosttranslationalModification disease BEFREE Diagnostic value of NKG2D promoter methylation in hepatitis B virus-associated hepatocellular carcinoma. 31411040 2019
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.050 AlteredExpression disease BEFREE Activated and hepatitis B virus (HBV)-specific T cells, particularly the CD4 fraction, expressed NKG2D ligands (NKG2DL), which were not found on T cells from healthy controls (p < 0.001). 28031333 2017
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.050 AlteredExpression disease BEFREE In conclusion, NKG2D regulates immune inflammation and anti-viral response partly through activation of NK cells during HBV infection. 28273905 2017
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.050 Biomarker disease BEFREE To explore the role of surface receptors natural killer group 2A (NKG2A) and natural killer group 2D (NKG2D) on CD3<sup>+</sup>CD8<sup>+</sup>T cells and CD3<sup>-</sup>CD56<sup>+</sup>NK cells in the progression of hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF), we measured the expression of NKG2A and NKG2D on the surface of these 2 types of circulating cells by flow cytometry in 3 groups. 27828717 2016
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.050 Biomarker disease BEFREE NKG2D co-stimulates intrahepatic CD8+ T cells and hepatitis B virus-specific CD8+ T cells. 19087227 2008