KLRC4-KLRK1, KLRC4-KLRK1 readthrough, 100528032

N. diseases: 246; N. variants: 5
Disease: Stomach Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.050 Biomarker disease BEFREE In conclusion, NKG2D-based CAR-T cells have potent in vivo and in vitro anti-tumor activities against gastric cancer and could be a new paradigm for patients with gastric cancer, either used alone or combined with chemotherapy. 30132099 2018
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.050 AlteredExpression disease BEFREE However, the roles of ULBP1 and NKG2D expression and associated immune responses in gastric cancer are unclear. 29391893 2018
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.050 AlteredExpression disease BEFREE The study aims to investigate the expression of NKG2D in gastric cancer in association with clinical prognosis and its biological function. 28433635 2017
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.050 AlteredExpression disease BEFREE Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility. 27002316 2016
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.050 AlteredExpression disease BEFREE NK cells from patients with lymph node metastasis expressed significantly lower levels of NKG2D than the NK cells from those without lymph node metastasis, and NKG2D expression on NK cells in gastric cancer tissue was significantly lower than that of circulating NK cells. 21626292 2012