DNM1L, dynamin 1 like, 10059

N. diseases: 273; N. variants: 15
Disease: Kidney Failure, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.040 PosttranslationalModification disease BEFREE ALR overexpression additionally had an impact on phosphorylation of Drp1 Ser637 during AKI. 31822044 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.040 Biomarker disease BEFREE Numb Depletion Promotes Drp1-Mediated Mitochondrial Fission and Exacerbates Mitochondrial Fragmentation and Dysfunction in Acute Kidney Injury. 29890853 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.040 Biomarker disease BEFREE Our results provide evidence that Drp1-depedent mitophagy has potential as renoprotective targets for the treatment of cisplatin-induced AKI. 28423497 2017
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.040 AlteredExpression disease BEFREE We recently found dysregulation of mitochondrial dynamics caused by increased Drp1 expression and cellular apoptosis of the heart in an experimental AKI animal model of renal ischemia-reperfusion. 27349577 2016