Disease: Melanoma, B16 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004565
Disease: Melanoma, B16
Melanoma, B16 		0.010 AlteredExpression disease BEFREE When the tumor reactivity of dominant clonotypic TCRs in each mouse was analyzed, 9 of 13 TCRs induced the secretion of IFNγ in response to, and showed killing of, B16F10 cells <i>in vitro</i>, and 2 of them showed strong antitumor activity <i>in vivo</i> Concerning their antigen specificity, 7 of them reacted to p15E peptide of endogenous murine leukemia virus-derived envelope glycoprotein 70, and the rest reacted to tumor-associated antigens expressed on EL4 lymphoma as well as B16 melanoma cells. 29475880 2018