PSC, Cholangitis, primary sclerosing, 100653366

N. diseases: 67; N. variants: 0
Disease: Non-alcoholic Fatty Liver Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0400966
Disease: Non-alcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease 		0.020 PosttranslationalModification disease BEFREE By comparing the signal transduction pathways involved in the identified core GENs, we found that the hepatocarcinogenesis through NAFLD&NASH was induced through DNA methylation of <i>HIST2H2BE</i>, <i>HSPB1</i>, <i>RPL30</i>, and <i>ALDOB</i> and the regulation of miR-21 and miR-122, and the hepatocarcinogenesis through PBC&PSC was induced through DNA methylation of <i>RPL23A</i>, <i>HIST2H2BE</i>, <i>TIMP1</i>, <i>IGF2</i>, <i>RPL30</i>, and <i>ALDOB</i> and the regulation of miR-29a, miR-21, and miR-122. 30344796 2018
CUI: C0400966
Disease: Non-alcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease 		0.020 Biomarker disease BEFREE Hepcidin mRNA levels were determined in liver biopsies obtained from 126 patients with HCV (n = 21), HBV (n = 23), autoimmune cholestatic disease (primary biliary cirrhosis and primary sclerosing cholangitis; PBC/PSC; n = 34), autoimmune hepatitis (AIH; n = 16) and non-alcoholic fatty liver disease (NAFLD; n = 32). 26270641 2015