Papillary thyroid carcinoma
|
0.340 |
GeneticVariation
|
disease |
BEFREE |
Our data suggest that SNP rs944289 predisposes to PTC through a previously uncharacterized, long intergenic noncoding RNA gene (PTCSC3) that has the characteristics of a tumor suppressor.
|
22586128 |
2012 |
Neoplasms
|
0.070 |
GeneticVariation
|
group |
BEFREE |
Our data suggest that SNP rs944289 predisposes to PTC through a previously uncharacterized, long intergenic noncoding RNA gene (PTCSC3) that has the characteristics of a tumor suppressor.
|
22586128 |
2012 |
Thyroid carcinoma
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Association of rs944289, which was previously known to confer risk for thyroid cancer, with FA, and the correlation between PTCSC3 and NRG1 expression demonstrates that predisposing genetic factors are partly common for benign and malignant thyroid tumors, and imply broader roles of the pathways they underlie in thyroid tumorigenesis, not limited to carcinogenesis.
|
25562676 |
2015 |
Malignant neoplasm of thyroid
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Association of rs944289, which was previously known to confer risk for thyroid cancer, with FA, and the correlation between PTCSC3 and NRG1 expression demonstrates that predisposing genetic factors are partly common for benign and malignant thyroid tumors, and imply broader roles of the pathways they underlie in thyroid tumorigenesis, not limited to carcinogenesis.
|
25562676 |
2015 |
Thyroid Neoplasm
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Association of rs944289, which was previously known to confer risk for thyroid cancer, with FA, and the correlation between PTCSC3 and NRG1 expression demonstrates that predisposing genetic factors are partly common for benign and malignant thyroid tumors, and imply broader roles of the pathways they underlie in thyroid tumorigenesis, not limited to carcinogenesis.
|
25562676 |
2015 |
Carcinogenesis
|
0.020 |
GeneticVariation
|
phenotype |
BEFREE |
Association of rs944289, which was previously known to confer risk for thyroid cancer, with FA, and the correlation between PTCSC3 and NRG1 expression demonstrates that predisposing genetic factors are partly common for benign and malignant thyroid tumors, and imply broader roles of the pathways they underlie in thyroid tumorigenesis, not limited to carcinogenesis.
|
25562676 |
2015 |
Papillary thyroid carcinoma
|
0.340 |
Biomarker
|
disease |
BEFREE |
Long noncoding RNA papillary thyroid carcinoma susceptibility candidate 3 (PTCSC3) is a novel lncRNA that was primarily detected in papillary thyroid carcinoma.
|
28187755 |
2017 |
Papillary thyroid carcinoma
|
0.340 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Our data suggest that SNP rs944289 predisposes to PTC through a previously uncharacterized, long intergenic noncoding RNA gene (PTCSC3) that has the characteristics of a tumor suppressor.
|
22586128 |
2012 |
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
LncRNA PTCSC3 is a known tumor suppressor, while its roles in other human diseases are unclear.
|
31196168 |
2019 |
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
Long noncoding RNA (lncRNA) PTCSC3 (hereafter PTCSC3 is used to represent lncRNA PTCSC3) inhibits glioma and thyroid cancer, indicating its potential tumor suppression function in other types of cancers.
|
31026090 |
2019 |
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
In vivo experiments verified the fact that overexpressed PTCSC3 inhibited tumor growth.
|
28513866 |
2017 |
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
LncRNA PTCSC3 is a tumor suppressor in thyroid cancer, and its role in drug resistance of anaplastic thyroid cancer (ATC) to chemotherapy drug doxorubicin was investigated in this study.
|
29561707 |
2018 |
Thyroid carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
LncRNA PTCSC3 is a tumor suppressor in thyroid cancer, and its role in drug resistance of anaplastic thyroid cancer (ATC) to chemotherapy drug doxorubicin was investigated in this study.
|
29561707 |
2018 |
Thyroid carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Previous studies have shown that PTCSC3 (Thyroid Carcinoma Susceptibility Candidate 3), miR-574-5p and Wnt/β-catenin were involved in PTC, but the potential pathogenic mechanism among them was still unclear.
|
28513866 |
2017 |
Thyroid carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
It is known that lncRNA PTCSC3 inhibits thyroid cancer and glioma and STAT3 promotes cancer development.
|
31171714 |
2019 |
Thyroid carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Long noncoding RNA (lncRNA) PTCSC3 (hereafter PTCSC3 is used to represent lncRNA PTCSC3) inhibits glioma and thyroid cancer, indicating its potential tumor suppression function in other types of cancers.
|
31026090 |
2019 |
Malignant neoplasm of thyroid
|
0.040 |
Biomarker
|
disease |
BEFREE |
LncRNA PTCSC3 is a tumor suppressor in thyroid cancer, and its role in drug resistance of anaplastic thyroid cancer (ATC) to chemotherapy drug doxorubicin was investigated in this study.
|
29561707 |
2018 |
Malignant neoplasm of thyroid
|
0.040 |
Biomarker
|
disease |
BEFREE |
Long noncoding RNA (lncRNA) PTCSC3 (hereafter PTCSC3 is used to represent lncRNA PTCSC3) inhibits glioma and thyroid cancer, indicating its potential tumor suppression function in other types of cancers.
|
31026090 |
2019 |
Malignant neoplasm of thyroid
|
0.040 |
Biomarker
|
disease |
BEFREE |
It is known that lncRNA PTCSC3 inhibits thyroid cancer and glioma and STAT3 promotes cancer development.
|
31171714 |
2019 |
Thyroid Neoplasm
|
0.040 |
Biomarker
|
disease |
BEFREE |
Long noncoding RNA (lncRNA) PTCSC3 (hereafter PTCSC3 is used to represent lncRNA PTCSC3) inhibits glioma and thyroid cancer, indicating its potential tumor suppression function in other types of cancers.
|
31026090 |
2019 |
Thyroid Neoplasm
|
0.040 |
Biomarker
|
disease |
BEFREE |
It is known that lncRNA PTCSC3 inhibits thyroid cancer and glioma and STAT3 promotes cancer development.
|
31171714 |
2019 |
Thyroid Neoplasm
|
0.040 |
Biomarker
|
disease |
BEFREE |
LncRNA PTCSC3 is a tumor suppressor in thyroid cancer, and its role in drug resistance of anaplastic thyroid cancer (ATC) to chemotherapy drug doxorubicin was investigated in this study.
|
29561707 |
2018 |
Glioma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Long noncoding RNA (lncRNA) PTCSC3 (hereafter PTCSC3 is used to represent lncRNA PTCSC3) inhibits glioma and thyroid cancer, indicating its potential tumor suppression function in other types of cancers.
|
31026090 |
2019 |
Glioma
|
0.030 |
Biomarker
|
disease |
BEFREE |
It is known that lncRNA PTCSC3 inhibits thyroid cancer and glioma and STAT3 promotes cancer development.
|
31171714 |
2019 |
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
PTCSC3 inhibits tumor growth and cancer cell stemness in gastric cancer by interacting with lncRNA Linc-pint.
|
31849528 |
2019 |