ACTR2, actin related protein 2, 10097

N. diseases: 45; N. variants: 1
Disease: Hirschsprung Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019569
Disease: Hirschsprung Disease
Hirschsprung Disease 		0.020 Biomarker disease BEFREE MPGES-1 derived PGE2 inhibits cell migration by regulating ARP2/3 in the pathogenesis of Hirschsprung disease. 30814036 2019
CUI: C0019569
Disease: Hirschsprung Disease
Hirschsprung Disease 		0.020 Biomarker disease BEFREE Our study demonstrates that the miR-24-1*/let-7a*-ARP2/3 complex-RAC isoforms pathway may represent a novel pathogenic mechanism for HSCR. 26991540 2016