KIF20A protein expression was highly correlated with International Federation of Gynecology and Obstetrics stage (<i>P</i>=0.008), lymph node metastasis (<i>P</i>=0.002), intraperitoneal metastasis (<i>P</i><0.001), vital status at last follow-up (<i>P</i><0.001), intraperitoneal recurrence (<i>P</i>=0.030), tumor recurrence (<i>P</i>=0.005), drug resistance (<i>P</i>=0.013), and ascites with tumor cells (<i>P</i><0.001).
Immunohistochemistry analysis in 169 cervical cancer cases revealed that increased KIF20A expression was strongly associated with human papillomavirus (HPV) infection (P = 0.008), clinical stage (P = 0.001), tumor recurrence (P = 0.016), vital status (P < 0.001), the property of the surgical margin (P = 0.032), the lymphovascular space involvement (P = 0.014), and pelvic lymph node metastasis (P = 0.001).