CDH13, cadherin 13, 1012

N. diseases: 205; N. variants: 47
Disease: Carcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 PosttranslationalModification phenotype BEFREE Role of CDH13 promoter methylation in the carcinogenesis, progression, and prognosis of colorectal cancer: A systematic meta-analysis under PRISMA guidelines. 28121942 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 AlteredExpression phenotype BEFREE The nuclear factor of kappa light polypeptide gene enhancer in B cells 1 (NFKB1) gene encodes p105 and p50 kD which are both subunits of the transcription factor NF-kB, involved in a wide variety of diseases and pathological states associated with inflammation, immunity, and tumorigenesis. 26563375 2016
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 PosttranslationalModification phenotype BEFREE Our study indicates that CDH13 methylation may play an important role in the carcinogenesis, development and progression of bladder cancer. 27578166 2016
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function. 26300007 2016
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 PosttranslationalModification phenotype BEFREE These results suggest that silencing of the CDH13 gene by aberrant promoter methylation and allelic deletion is associated with tumorigenesis in a subset of B-DLCL. 15289870 2004
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 PosttranslationalModification phenotype BEFREE Our results suggest that CDH13 expression is frequently silenced by aberrant methylation in colorectal cancers and adenomas and that methylation of CDH13 commences at an early stage of multistep colorectal tumorigenesis. 12067979 2002