CDH13, cadherin 13, 1012

N. diseases: 205; N. variants: 47
Disease: Carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.080 AlteredExpression disease BEFREE RT-PCR was used to measure CDH13 expression in lung cancer A549 and A549/DDP cells with or without 5-Aza-CdR intervention. 30344726 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.080 PosttranslationalModification disease BEFREE Hence, our study identified a strong association between CDH13 gene promoter methylation and LC and highlighted a promising potential for CDH13 methylation in LC risk prediction. 25735345 2015
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.080 GeneticVariation disease BEFREE The methylation status of 6 genes, including a candidate tumor suppressor gene (BLU), the cadherin 13 gene (CDH13), the fragile histidine triad gene (FHIT), the cell cycle control gene p16, the retinoic acid receptor beta gene (RARbeta), and the Ras association domain family 1 gene (RASSF1A), was examined in plasma samples, corresponding tumor tissues, and normal lung tissues from a group of 63 patients with lung cancer and in plasma samples from 36 cancer-free individuals. 17876837 2007
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.080 Biomarker disease BEFREE Although the aberrant methylation of E-cadherin (CDH1) or H-cadherin (CDH13) genes has been reported in lung cancer, to the authors' knowledge, the relation between the concurrent hypermethylation in E-cadherin and H-cadherin has not been explored to date. 17960794 2007
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.080 PosttranslationalModification disease BEFREE Methylation status of p16(INK4a), RASSF1A, APC, RARbeta, and CDH13, frequently methylated in lung cancer, was determined by methylation-specific PCR and the degree of methylation was defined as the methylation index. 16452191 2006
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.080 PosttranslationalModification disease BEFREE In conclusion, the frequency of p16INK4A or CDH13 hypermethylation in patient serum, together with evidence of their early occurrence in lung cancerogenesis and the total lack of methylation in serum from healthy individuals, offer a promising tool for non invasive early detection of lung cancer. 16222700 2006
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.080 PosttranslationalModification disease BEFREE Aberrant methylation of H-cadherin (CDH13) promoter is associated with tumor progression in primary nonsmall cell lung carcinoma. 16177988 2005
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.080 GeneticVariation disease BEFREE Since the H-cadherin (CDH13) gene has been isolated and mapped to this common region of allelic loss, we have investigated this gene in human lung cancer. 9737784 1998