PLXNC1, plexin C1, 10154

N. diseases: 29; N. variants: 12
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE Our results demonstrated that lncRNA CASC2 can promote PLXNC1 expression by sponging miR-181a, thereby inhibiting the proliferation and invasion of melanoma cells, indicating that lncRNA CASC2 functions via the miR-181a/PLXNC1 axis in melanoma. 29514220 2018
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE These data identify Plexin C1 as a potential tumor suppressor protein in melanoma progression, and suggest that loss of Plexin C1 expression may promote melanoma invasion and metastasis through loss of inhibitory signaling on cofilin activation. 18987670 2009
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease LHGDN Semaphorin 7a promotes spreading and dendricity in human melanocytes through beta1-integrins. 17671519 2008