CDK2, cyclin dependent kinase 2, 1017

N. diseases: 270; N. variants: 4
Disease: Pineal Gland Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031941
Disease: Pineal Gland Neoplasm
Pineal Gland Neoplasm 		0.010 Biomarker disease BEFREE Pharmacologic inhibition of CDK2 in an in vivo model of pineal tumor decreased proliferation and promoted early senescence, and it also decreased tumor penetrance and prolonged time to tumor formation in animals lacking p53. 25149358 2015