CDK4, cyclin dependent kinase 4, 1019

N. diseases: 433; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206642
Disease: Parosteal Osteosarcoma
Parosteal Osteosarcoma
0.020 AlteredExpression disease BEFREE Retrospective analysis of MDM2/CDK4 expression/amplification using immunostaining, multiplex quantitative polymerase chain reaction (MQPCR) and fluorescence in situ hybridization (FISH) were studied on 14 patients with recurrent POS. 31634336 2019
CUI: C0206642
Disease: Parosteal Osteosarcoma
Parosteal Osteosarcoma
0.020 AlteredExpression disease BEFREE This retrospective analysis has demonstrated that MDM2 and CDK4 are very rarely expressed in primary and recurrent periosteal osteosarcomas and therefore do not appear to be molecules central to the control of cancer development, growth, and progression in periosteal osteosarcoma. 25680902 2015