ADAM10, ADAM metallopeptidase domain 10, 102

N. diseases: 224; N. variants: 27
Disease: ALZHEIMER DISEASE 18 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.600 GeneticVariation disease UNIPROT ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function. 24055016 2013
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.600 GeneticVariation disease UNIPROT Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. 19608551 2009
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.600 Biomarker disease CTD_human
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.600 SusceptibilityMutation disease CLINVAR