CDK5, cyclin dependent kinase 5, 1020

N. diseases: 204; N. variants: 3
Disease: Tactile Allodynia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751213
Disease: Tactile Allodynia
Tactile Allodynia 		0.010 PosttranslationalModification phenotype BEFREE These findings unveil a novel mechanism for how phosphorylation may regulate Cav3.2 channels and suggest that increased channel activity by Cdk5-mediated phosphorylation after SNL contributes nerve injury-induced tactile allodynia.<b>Significance statement</b>Neuropathic pain is a current public health challenge. 31744861 2020