CDK6, cyclin dependent kinase 6, 1021

N. diseases: 266; N. variants: 27
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma
0.020 AlteredExpression disease BEFREE These results indicate that ultrasound-mediated PTX-miR-34a-MBs synergistically inhibit the growth of cervical cancer via the upregulation of miR-34a and downregulation of Bcl-2 and CDK6. 31093891 2020
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma
0.020 GeneticVariation disease BEFREE CDK6 rs8179 and rs42033 were correlated to the decreased risk of cervical cancer in Uyghurs under the allele model (rs8179 and rs42033: OR = 0.60, 95% CI: 0.37-0.99, p = 0.043) and log-additive model (rs8179 and rs42033: OR = 0.62, 95% CI: 0.38-1.00, p = 0.047). 30829464 2019