CDK7, cyclin dependent kinase 7, 1022

N. diseases: 89; N. variants: 1
Disease: Addictive Behavior ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 AlteredExpression phenotype BEFREE THZ1 reveals CDK7-dependent transcriptional addictions in pancreatic cancer. 30692639 2019
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 Biomarker phenotype BEFREE Preclinical Efficacy and Molecular Mechanism of Targeting CDK7-Dependent Transcriptional Addiction in Ovarian Cancer. 28572168 2017
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 Biomarker phenotype BEFREE We conclude that CDK7 mediates transcriptional addiction to a vital cluster of genes in TNBC and CDK7 inhibition may be a useful therapy for this challenging cancer. 26406377 2015
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 Biomarker phenotype BEFREE Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor. 25490451 2014