CDK7, cyclin dependent kinase 7, 1022

N. diseases: 89; N. variants: 1
Disease: Pancreatic carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.030 AlteredExpression disease BEFREE In conclusion, Identification of CDK7-dependent transcriptional addiction in PDACs provides a potent therapeutic strategy that targets highly aggressive pancreatic cancer. 30692639 2019
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.030 Biomarker disease BEFREE Overexpression of serine/threonine-protein kinase-1 in pancreatic cancer tissue: Serine/threonine-protein kinase-1 knockdown increases the chemosensitivity of pancreatic cancer cells. 25760059 2015
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.030 GeneticVariation disease BEFREE Germline mutations in the BRCA2, CDKN2A/p16, hMSH2, hMLH1, hPMS1, hPMS2, LKB1/STK1, and PRSS1 genes have been associated with increased risk for pancreatic cancer. 12120238 2001