CDKN1A, cyclin dependent kinase inhibitor 1A, 1026

N. diseases: 490; N. variants: 17
Disease: Intestinal metaplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia 		0.020 AlteredExpression phenotype BEFREE In contrast, H. pylori induced the expression of the CDK inhibitor p21(WAF-1/cip1), and the homeobox transcription factor, Cdx2, an early marker of intestinal metaplasia of the stomach epithelium. 16473539 2006
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia 		0.020 GeneticVariation phenotype BEFREE The combination of p53 codon 72 variation with the p21(WAF1/CIP1) haplotype further distinguished the risk of GC from IM precancerous lesion (OR = 9.31, 95% CI = 1.77-48.85, P = 0.08). 15240512 2004