CDKN1B, cyclin dependent kinase inhibitor 1B, 1027

N. diseases: 373; N. variants: 7
Disease: Prostatic Intraepithelial Neoplasias ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0282612
Disease: Prostatic Intraepithelial Neoplasias
Prostatic Intraepithelial Neoplasias 		0.320 Biomarker disease BEFREE These data suggest that a p27(Kip1)-driven checkpoint limits progression of PIN to CaP. 18691549 2008
CUI: C0282612
Disease: Prostatic Intraepithelial Neoplasias
Prostatic Intraepithelial Neoplasias 		0.320 Biomarker disease BEFREE Strong p27Kip1 staining was uniformly seen in benign prostatic epithelial components in all tumor sections. p27Kip1 staining was reduced in most prostate cancers and was variable in prostatic intraepithelial neoplasia. 9458103 1998