CDKN2A, cyclin dependent kinase inhibitor 2A, 1029

N. diseases: 1314; N. variants: 146
Disease: Acute monocytic leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.040 AlteredExpression disease BEFREE Immunohistochemically, AMLs demonstrated focal MDM2 expression (40% of cases) and focal/diffuse expression of p16 (60%). 29432785 2018
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.040 Biomarker disease BEFREE Reactivating the ARF-p53 axis in AML cells by targeting ULF. 20699639 2010
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.040 AlteredExpression disease BEFREE AML at older age: age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance. 19667402 2009
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.040 PosttranslationalModification disease BEFREE These results revealed the frequent methylation of p16 and p15 genes in B-ALL and AML despite a low frequency of p16 and p15 deletions and mutations in these leukemias. 10634644 2000