ADAR, adenosine deaminase RNA specific, 103

N. diseases: 256; N. variants: 32
Disease: CML progression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1739405
Disease: CML progression
CML progression 		0.010 AlteredExpression disease BEFREE In this study, whole-transcriptome sequencing of normal, chronic phase, and serially transplantable blast crisis chronic myeloid leukemia (CML) progenitors revealed increased IFN-γ pathway gene expression in concert with BCR-ABL amplification, enhanced expression of the IFN-responsive ADAR1 p150 isoform, and a propensity for increased adenosine-to-inosine RNA editing during CML progression. 23275297 2013